Literature DB >> 16814486

Evaluation of the antitussive effect of stigma and petals of saffron (Crocus sativus) and its components, safranal and crocin in guinea pigs.

Hossein Hosseinzadeh1, Jafar Ghenaati.   

Abstract

The antitussive activity of Crocus sativus stigma and petal extracts and its components, safranal and crocin, was evaluated using the nebolized solution of citric acid 20% in guinea pigs. The extract and agents were injected intraperitoneally. The ethanolic extract of C. sativus (100-800 mg/kg) and safranal (0.25-0.75 ml/kg) reduced the number of cough. The ethanolic and aqueous extracts of petal and crocin did not show antitussive activity.

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Year:  2006        PMID: 16814486     DOI: 10.1016/j.fitote.2006.04.012

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  32 in total

Review 1.  Pharmacokinetic Properties of Saffron and its Active Components.

Authors:  Azar Hosseini; Bibi Marjan Razavi; Hossein Hosseinzadeh
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2018-08       Impact factor: 2.441

2.  Crocus sativus L.: A comprehensive review.

Authors:  R Srivastava; H Ahmed; R K Dixit; S A Saraf
Journal:  Pharmacogn Rev       Date:  2010-07

3.  Use of in vitro assays to assess the potential antiproliferative and cytotoxic effects of saffron (Crocus sativus L.) in human lung cancer cell line.

Authors:  Saeed Samarghandian; Mohammad Hossein Boskabady; Saideh Davoodi
Journal:  Pharmacogn Mag       Date:  2010-10       Impact factor: 1.085

4.  Bacillus subtilis FZB24 affects flower quantity and quality of saffron (Crocus sativus).

Authors:  Mahmoud Sharaf-Eldin; Shereen Elkholy; José-Antonio Fernández; Helmut Junge; Ronald Cheetham; José Guardiola; Pamela Weathers
Journal:  Planta Med       Date:  2008-07-11       Impact factor: 3.352

5.  New minor glycoside components from saffron.

Authors:  Nguyen Huu Tung; Yukihiro Shoyama
Journal:  J Nat Med       Date:  2012-11-21       Impact factor: 2.343

Review 6.  Saffron: A potential drug-supplement for severe acute respiratory syndrome coronavirus (COVID) management.

Authors:  Amjad M Husaini; Khan Nadiya Jan; Gowher A Wani
Journal:  Heliyon       Date:  2021-05-14

Review 7.  A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov.

Authors:  Rambod Abiri; Hazandy Abdul-Hamid; Oksana Sytar; Ramin Abiri; Eduardo Bezerra de Almeida; Surender K Sharma; Victor P Bulgakov; Randolph R J Arroo; Sonia Malik
Journal:  Molecules       Date:  2021-06-24       Impact factor: 4.411

8.  Cardioprotective effect of saffron extract and safranal in isoproterenol-induced myocardial infarction in wistar rats.

Authors:  Roya Mehdizadeh; Mohammad-Reza Parizadeh; Ali-Reza Khooei; Soghra Mehri; Hossein Hosseinzadeh
Journal:  Iran J Basic Med Sci       Date:  2013-01       Impact factor: 2.699

9.  The potential effect of the extract of Crocus sativus and safranal on the total and differential white blood cells of ovalbumin-sensitized guinea pigs.

Authors:  G Bayrami; M H Boskabady
Journal:  Res Pharm Sci       Date:  2012-10

10.  Affinity-based target deconvolution of safranal.

Authors:  Hossein Hosseinzadeh; Soghra Mehri; Mohammad Mahdi Abolhassani; Mohammad Ramezani; Amirhossein Sahebkar; Khalil Abnous
Journal:  Daru       Date:  2013-03-20       Impact factor: 3.117

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