Literature DB >> 16813930

The magnitude of fetal renal pelvic dilatation can identify obstructive postnatal hydronephrosis, and direct postnatal evaluation and management.

Douglas E Coplen1, Paul F Austin, Yan Yan, Valerie M Blanco, Jeffrey M Dicke.   

Abstract

PURPOSE: Up to 1% of prenatal ultrasounds will detect fetal renal pelvic dilatation. We sought to evaluate and determine whether fetal renal pelvic measurements may appropriately direct prenatal counseling and postnatal evaluation and management.
MATERIALS AND METHODS: We performed a retrospective analysis of prospectively collected measurements of anteroposterior renal pelvic dilatation obtained at a single fetal maternal medicine center between 1990 and 2003. Fetuses with renal pelvic dilatation 4 mm or greater at less than 33 weeks of gestation, or 7 mm or greater at more than 33 weeks of gestation were evaluated postnatally at a single pediatric urology center. Infants with renal pelvic dilatation were evaluated with ultrasound, voiding cystourethrograms and renal scintigraphy. Renal obstruction was the main outcome measure assessed. Obstruction was defined as the need for surgery and was not based on the renal scan drainage time. Indications for surgery included declining function and increasing hydronephrosis.
RESULTS: There were 257 neonates with prenatally detected renal pelvic dilatation. A mean maximum prenatal renal pelvic dilatation of 11.8 mm was seen in 195 patients with nonobstructive dilatation. In the 62 patients with obstruction there was a nearly 2-fold increase in the mean renal pelvic dilatation (22.3 mm), which was statistically significant. Receiver operating characteristic analysis revealed that when 15 mm renal pelvic dilatation is used as a threshold it correctly discriminates obstruction in at least 80% of fetuses with a sensitivity of 73% and a specificity of 82%.
CONCLUSIONS: The magnitude of fetal renal pelvic dilatation is predictive of obstruction. Our results suggest that 15 mm renal pelvic dilatation represents a significant threshold. Receiver operating characteristic analysis provides a useful guide for prenatal counseling and may help to direct the postnatal evaluation.

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Year:  2006        PMID: 16813930     DOI: 10.1016/j.juro.2006.03.079

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  27 in total

1.  Outcome and management of isolated severe renal pelvis dilatation detected at postnatal screening.

Authors:  Carmelo Mamì; Antonella Palmara; Antonina Paolata; Teresa Marrone; Lucia Marseglia; Luca F Bertè; Francesco Arena
Journal:  Pediatr Nephrol       Date:  2010-06-17       Impact factor: 3.714

Review 2.  Management of fetal hydronephrosis.

Authors:  Jenny Yiee; Duncan Wilcox
Journal:  Pediatr Nephrol       Date:  2007-08-02       Impact factor: 3.714

Review 3.  Mild fetal renal pelvis dilatation: much ado about nothing?

Authors:  Daljit K Hothi; Angie S Wade; Ruth Gilbert; Paul J D Winyard
Journal:  Clin J Am Soc Nephrol       Date:  2008-11-05       Impact factor: 8.237

4.  Variability Over Time of Normal-Sized Fetal Renal Pelvis During the Second Trimester Scan.

Authors:  Maria Aurora Hernandez Røset; Harm-Gerd Karl Blaas; Tove Anita Fagerli; Torbjørn Moe Eggebø
Journal:  Ultrasound Int Open       Date:  2017-09-26

5.  Diagnostic accuracy of neonatal kidney ultrasound in children having antenatal hydronephrosis without ureter and bladder abnormalities.

Authors:  Pornpimol Rianthavorn; Sorawan Limwattana
Journal:  World J Urol       Date:  2015-01-07       Impact factor: 4.226

6.  Characterizing upper urinary tract dilation on ultrasound: a survey of North American pediatric radiologists' practices.

Authors:  David W Swenson; Kassa Darge; Sonja I Ziniel; Jeanne S Chow
Journal:  Pediatr Radiol       Date:  2014-11-25

7.  [Congenital dilatation of the upper urinary tract : Current diagnostic and treatment concepts].

Authors:  R Beetz
Journal:  Urologe A       Date:  2018-08       Impact factor: 0.639

8.  Should prenatal hydronephrosis that resolves before birth be followed postnatally? Analysis and comparison to persistent prenatal hydronephrosis.

Authors:  Patrick L Scarborough; Elizabeth Ferrara; Douglas W Storm
Journal:  Pediatr Nephrol       Date:  2015-04-01       Impact factor: 3.714

Review 9.  Mild to moderate postnatal hydronephrosis--grading systems and management.

Authors:  Matthew D Timberlake; C D Anthony Herndon
Journal:  Nat Rev Urol       Date:  2013-08-20       Impact factor: 14.432

Review 10.  Antenatally diagnosed hydronephrosis: current postnatal management.

Authors:  Michael T Davenport; Paul A Merguerian; Martin Koyle
Journal:  Pediatr Surg Int       Date:  2013-01-17       Impact factor: 1.827

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