| Literature DB >> 16813753 |
Céline Méhats1, Thomas Schmitz, Michelle Breuiller-Fouché, Marie-Josèphe Leroy, Dominique Cabrol.
Abstract
Sildenafil citrate is a phosphodiesterase 5-selective inhibitor used successfully in treating erectile dysfunction. High doses of sildenafil can inhibit myometrial contractions. However, no study has demonstrated a role for phosphodiesterase 5 in myometrial contractility. No clinical trial using sildenafil to promote uterine relaxation should be initiated based on the currently available data.Entities:
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Year: 2006 PMID： 16813753 DOI： 10.1016/j.ajog.2005.12.006
Source DB: PubMed Journal: Am J Obstet Gynecol ISSN： 0002-9378 Impact factor: 8.661