Literature DB >> 16813745

Postmenopausal hormone therapy increases use of health services: experience from the Estonian Postmenopausal Hormone Therapy Trial [ISRCTN35338757].

Piret Veerus1, Krista Fischer, Sirpa-Liisa Hovi, Matti Hakama, Mati Rahu, Elina Hemminki.   

Abstract

OBJECTIVE: This study was undertaken to compare utilization of health services and health care costs in a randomized hormone therapy trial. STUDY
DESIGN: A total of 1823 healthy postmenopausal women aged 50 to 64 years at the time of sampling were allocated to combined continuous hormone therapy or placebo or no treatment. The analysis was based on routinely collected electronic data in the Estonian Health Insurance Fund database during a follow-up period from 2 to 5 years.
RESULTS: In the nonblind subtrial, the number of all health care visits was 10% higher and the number of visits to family practitioners 16% higher per person-year in the hormone therapy arm. Per person-year, the number of vaginal sonograms was 14% and the number of electrocardiograms 19% higher in the nonblind hormone therapy arm. Outpatient health care costs and drug expenses were higher in the nonblind hormone therapy arm. In the blind subtrial, the number of gynecologic operations, vaginal sonograms and total health care costs was higher in the hormone therapy arm.
CONCLUSION: Hormone therapy caused additional expenses on health care.

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Mesh:

Year:  2006        PMID: 16813745     DOI: 10.1016/j.ajog.2005.12.037

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  4 in total

1.  Results from a blind and a non-blind randomised trial run in parallel: experience from the Estonian Postmenopausal Hormone Therapy (EPHT) Trial.

Authors:  Piret Veerus; Krista Fischer; Matti Hakama; Elina Hemminki
Journal:  BMC Med Res Methodol       Date:  2012-04-04       Impact factor: 4.615

2.  Effect of characteristics of women on attendance in blind and non-blind randomised trials: analysis of recruitment data from the EPHT Trial.

Authors:  Piret Veerus; Krista Fischer; Elina Hemminki; Sirpa-Liisa Hovi; Matti Hakama
Journal:  BMJ Open       Date:  2016-10-18       Impact factor: 2.692

3.  Variability of bothersome menopausal symptoms over time--a longitudinal analysis using the Estonian postmenopausal hormone therapy trial (EPHT).

Authors:  Elina Hemminki; Elena Regushevskaya; Riitta Luoto; Piret Veerus
Journal:  BMC Womens Health       Date:  2012-12-21       Impact factor: 2.809

4.  Symptom reporting and quality of life in the Estonian Postmenopausal Hormone Therapy Trial.

Authors:  Piret Veerus; Krista Fischer; Sirpa-Liisa Hovi; Helle Karro; Mati Rahu; Elina Hemminki
Journal:  BMC Womens Health       Date:  2008-03-26       Impact factor: 2.809

  4 in total

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