Literature DB >> 1681264

Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis.

J Kjeldsen-Kragh1, M Haugen, C F Borchgrevink, E Laerum, M Eek, P Mowinkel, K Hovi, O Førre.   

Abstract

Fasting is an effective treatment for rheumatoid arthritis, but most patients relapse on reintroduction of food. The effect of fasting followed by one year of a vegetarian diet was assessed in a randomised, single-blind controlled trial. 27 patients were allocated to a four-week stay at a health farm. After an initial 7-10 day subtotal fast, they were put on an individually adjusted gluten-free vegan diet for 3.5 months. The food was then gradually changed to a lactovegetarian diet for the remainder of the study. A control group of 26 patients stayed for four weeks at a convalescent home, but ate an ordinary diet throughout the whole study period. After four weeks at the health farm the diet group showed a significant improvement in number of tender joints, Ritchie's articular index, number of swollen joints, pain score, duration of morning stiffness, grip strength, erythrocyte sedimentation rate, C-reactive protein, white blood cell count, and a health assessment questionnaire score. In the control group, only pain score improved score. In the control group, only pain score improved significantly. The benefits in the diet group were still present after one year, and evaluation of the whole course showed significant advantages for the diet group in all measured indices. This dietary regimen seems to be a useful supplement to conventional medical treatment of rheumatoid arthritis.

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Year:  1991        PMID: 1681264     DOI: 10.1016/0140-6736(91)91770-u

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  76 in total

1.  Mediterranean diet intervention in rheumatoid arthritis.

Authors:  J Kjeldsen-Kragh
Journal:  Ann Rheum Dis       Date:  2003-03       Impact factor: 19.103

2.  Leptin in intestinal inflammation: good and bad gut feelings.

Authors:  G Matarese; R I Lechler
Journal:  Gut       Date:  2004-07       Impact factor: 23.059

3.  EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT).

Authors:  B Combe; R Landewe; C Lukas; H D Bolosiu; F Breedveld; M Dougados; P Emery; G Ferraccioli; J M W Hazes; L Klareskog; K Machold; E Martin-Mola; H Nielsen; A Silman; J Smolen; H Yazici
Journal:  Ann Rheum Dis       Date:  2006-01-05       Impact factor: 19.103

Review 4.  Rheumatoid arthritis, fasting, diet and bacteria: myths and enthusiasm.

Authors:  M T Nenonen
Journal:  Clin Rheumatol       Date:  1998       Impact factor: 2.980

Review 5.  From Religion to Secularism: the Benefits of Fasting.

Authors:  Carla Venegas-Borsellino; Robert G Martindale
Journal:  Curr Nutr Rep       Date:  2018-07-09

6.  Vegetarian-Based Dietary Patterns and their Relation with Inflammatory and Immune Biomarkers: A Systematic Review and Meta-Analysis.

Authors:  Joel C Craddock; Elizabeth P Neale; Gregory E Peoples; Yasmine C Probst
Journal:  Adv Nutr       Date:  2019-05-01       Impact factor: 8.701

7.  Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.

Authors:  Stefan Jordan; Navpreet Tung; Maria Casanova-Acebes; Christie Chang; Claudia Cantoni; Dachuan Zhang; Theresa H Wirtz; Shruti Naik; Samuel A Rose; Chad N Brocker; Anastasiia Gainullina; Daniel Hornburg; Sam Horng; Barbara B Maier; Paolo Cravedi; Derek LeRoith; Frank J Gonzalez; Felix Meissner; Jordi Ochando; Adeeb Rahman; Jerry E Chipuk; Maxim N Artyomov; Paul S Frenette; Laura Piccio; Marie-Luise Berres; Emily J Gallagher; Miriam Merad
Journal:  Cell       Date:  2019-08-22       Impact factor: 41.582

Review 8.  Fasting: molecular mechanisms and clinical applications.

Authors:  Valter D Longo; Mark P Mattson
Journal:  Cell Metab       Date:  2014-01-16       Impact factor: 27.287

9.  Calorie restriction prevents the occlusive coronary vascular disease of autoimmune (NZW x BXSB)F1 mice.

Authors:  H Mizutani; R W Engelman; K Kinjoh; Y Kurata; S Ikehara; Y Matsuzawa; R A Good
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

10.  The influence of fast and vegetarian diet on parameters of nutritional status in patients with rheumatoid arthritis.

Authors:  M A Haugen; J Kjeldsen-Kragh; N Skakkebaek; S Landaas; O Sjaastad; P Movinkel; O Førre
Journal:  Clin Rheumatol       Date:  1993-03       Impact factor: 2.980

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