Literature DB >> 16810063

p16-Positive small cell neuroendocrine carcinoma of the endometrium.

Frank Melgoza1, Wendy R Brewster, Sharon Wilczynski, Joanne Rutgers.   

Abstract

We report herein a small cell neuroendocrine carcinoma of the endometrium that extended to the cervix and showed strong immunohistochemical staining for p16. The p16 staining raised the possibility of a human papillomavirus (HPV)-related tumor, because in the cervix, a positive p16 immunohistochemical stain is presumptive evidence of HPV. However, the current case was HPV negative. We discuss the molecular pathogenesis of non-HPV-related increased p16 expression.

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Year:  2006        PMID： 16810063     DOI： 10.1097/01.pgp.0000189242.11404.ae

Source DB:  PubMed          Journal:  Int J Gynecol Pathol        ISSN： 0277-1691            Impact factor:   2.762


  5 in total

Review 1.  Pathology of Neuroendocrine Tumours of the Female Genital Tract.

Authors:  Brooke E Howitt; Paul Kelly; W Glenn McCluggage
Journal:  Curr Oncol Rep       Date:  2017-09       Impact factor: 5.075

2.  Small cell carcinoma of the endometrium: a case report with emphasis on the cytological features.

Authors:  Mitsuaki Ishida; Nozomi Iwamoto; Tetsuya Nakagawa; Shouji Kaku; Muneo Iwai; Akiko Kagotani; Kentarou Takahashi; Takashi Murakami; Hidetoshi Okabe
Journal:  Int J Clin Exp Pathol       Date:  2014-05-15

3.  Small cell neuroendocrine carcinoma of the oropharynx harbouring oncogenic HPV-infection.

Authors:  Timothy Bates; Andrew McQueen; Muhammad Shahid Iqbal; Charles Kelly; Max Robinson
Journal:  Head Neck Pathol       Date:  2013-07-10

4.  Neuroendocrine Carcinoma of the Endometrium: A Clinicopathologic Study of 25 Cases.

Authors:  Cady E Pocrnich; Preetha Ramalingam; Elizabeth D Euscher; Anais Malpica
Journal:  Am J Surg Pathol       Date:  2016-05       Impact factor: 6.394

5.  P16INK4A Immunohistochemistry as a Gold Standard for Cervical Cancer and Precursor Lesions Screening.

Authors:  Mahdieh Farzanehpour; Ahad Muhammadnejad; Setareh Akhavan; Amir Nader Emami Razavi; Somayeh Jalilvand; Vahid Salimi; Ebrahim Faghihloo; Ehsan Kakavandi; Mohammad Farahmand; Mohammad Shayestehpour; Farzad Babakhani; Talat Mokhtari Azad
Journal:  Iran J Public Health       Date:  2020-02       Impact factor: 1.429
  5 in total

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