Literature DB >> 16809990

Factors affecting perioperative transfusion decisions in patients with coronary artery disease undergoing coronary artery bypass surgery.

Nadine Shehata1, Kumanan Wilson, C David Mazer, George Tomlinson, David Streiner, Paul Hebert, Gary Naglie.   

Abstract

BACKGROUND: A high proportion of patients having cardiac bypass surgery receive erythrocyte transfusions. Decisions about when to transfuse patients having surgery for coronary artery disease may impact on erythrocyte utilization and patient morbidity and mortality. There are no published data about the factors that influence physicians' decisions to transfuse erythrocytes to these patients. The objectives of this study were to determine the hemoglobin concentration for transfusion and the factors that influence physicians' perioperative transfusion decisions for coronary artery bypass patients.
METHODS: The authors conducted a cross-sectional study using pretested, self-administered, mailed questionnaires sent in 2004 to all cardiac surgeons and anesthesiologists in Canada who participate in coronary artery bypass surgery. The questionnaire included four intraoperative and four postoperative vignettes. Factors assessed included patient age, sex, cardiac index, and myocardial ischemia.
RESULTS: The response rates were 70% (345 of 489) for the intraoperative and 61% (297 of 489) for the postoperative case scenarios. The mean hemoglobin concentrations for transfusion were 7.0 g/dl for the intraoperative case scenarios and 7.2 g/dl for the postoperative case scenarios. Older age, the presence of myocardial ischemia, and a low cardiac index were factors that increased the hemoglobin concentration for transfusion (P < 0.0001). Physicians ranked myocardial ischemia as the most significant factor affecting their transfusion decisions.
CONCLUSIONS: Factors such as the presence of a low cardiac index, myocardial ischemia, and older age increase the hemoglobin concentrations at which physicians transfuse coronary bypass surgery patients. Future studies are required to elucidate whether transfusions based on these variables affect patient morbidity and mortality.

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Year:  2006        PMID: 16809990     DOI: 10.1097/00000542-200607000-00008

Source DB:  PubMed          Journal:  Anesthesiology        ISSN: 0003-3022            Impact factor:   7.892


  2 in total

1.  The Role of Platelet Function Analyzer Testing in Cardiac Surgery Transfusion Management.

Authors:  Dejana Bogdanic; Nenad Karanovic; Jela Mratinovic-Mikulandra; Branka Paukovic-Sekulic; Dijana Brnic; Ivanka Marinovic; Diana Nonkovic; Nikolina Bogdanic
Journal:  Transfus Med Hemother       Date:  2017-02-01       Impact factor: 3.747

2.  Predictors of allogenic blood transfusion in elective cardiac surgery after preoperative autologous blood donation.

Authors:  Yoshiyuki Takami; Hiroshi Masumoto
Journal:  Surg Today       Date:  2009-03-25       Impact factor: 2.549

  2 in total

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