Literature DB >> 16809037

Macrolactin N, a new peptide deformylase inhibitor produced by Bacillus subtilis.

Jung-Sung Yoo1, Chang-Ji Zheng, Sangku Lee, Jin-Hwan Kwak, Won-Gon Kim.   

Abstract

A new 24-membered ring lactone, macrolactin N, was isolated from a culture broth of Bacillus subtilis and its structure was established by various spectral analysis. Macrolactin N inhibited Staphylococcus aureus peptide deformylase with an IC50 value of 7.5 microM and also showed antibacterial activity against Escherichia coli and S. aureus.

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Year:  2006        PMID： 16809037     DOI： 10.1016/j.bmcl.2006.06.058

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

1.  Insights from ligand and structure based methods in virtual screening of selective Ni-peptide deformylase inhibitors.

Authors:  Ravi Shekar Ananthula; Muttineni Ravikumar; S K Mahmood; M N S Pavan Kumar
Journal:  J Mol Model       Date:  2011-05-12       Impact factor: 1.810

2.  Drug forecast - the peptide deformylase inhibitors as antibacterial agents.

Authors:  David R P Guay
Journal:  Ther Clin Risk Manag       Date:  2007-08       Impact factor: 2.423

3.  Genome analysis of Bacillus amyloliquefaciens Subsp. plantarum UCMB5113: a rhizobacterium that improves plant growth and stress management.

Authors:  Adnan Niazi; Shahid Manzoor; Shashidar Asari; Sarosh Bejai; Johan Meijer; Erik Bongcam-Rudloff
Journal:  PLoS One       Date:  2014-08-13       Impact factor: 3.240

4.  Complete Genome Sequence of Bacillus subtilis GQJK2, a Plant Growth-Promoting Rhizobacterium with Antifungal Activity.

Authors:  Jinjin Ma; Hu Liu; Chengqiang Wang; Zhilin Xia; Kai Liu; Qihui Hou; Yuhuan Li; Tongrui Zhang; Haide Wang; Beibei Wang; Yun Wang; Ruofei Ge; Baochao Xu; Gan Yao; Zhensheng Jiang; Wentong Hou; Yanqin Ding; Binghai Du
Journal:  Genome Announc       Date:  2017-06-01

5.  Selection of sponge-associated bacteria with high potential for the production of antibacterial compounds.

Authors:  Walter Balansa; Yang Liu; Abha Sharma; Sanja Mihajlovic; Christoph Hartwig; Benedikt Leis; Frets Jonas Rieuwpassa; Frans Gruber Ijong; Heike Wägele; Gabriele M König; Till F Schäberle
Journal:  Sci Rep       Date:  2020-11-12       Impact factor: 4.379

Review 6.  Diversity of secondary metabolites from marine Bacillus species: chemistry and biological activity.

Authors:  Muhammad Abdul Mojid Mondol; Hee Jae Shin; Mohammad Tofazzal Islam
Journal:  Mar Drugs       Date:  2013-08-12       Impact factor: 5.118

7.  Diversity and Antimicrobial Activity of Vietnamese Sponge-Associated Bacteria.

Authors:  Ton That Huu Dat; Nguyen Thi Kim Cuc; Pham Viet Cuong; Hauke Smidt; Detmer Sipkema
Journal:  Mar Drugs       Date:  2021-06-22       Impact factor: 5.118

8.  Genomic, Antimicrobial, and Aphicidal Traits of Bacillus velezensis ATR2, and Its Biocontrol Potential against Ginger Rhizome Rot Disease Caused by Bacillus pumilus.

Authors:  Leiqin Liang; Yajuan Fu; Sangsang Deng; Yan Wu; Meiying Gao
Journal:  Microorganisms       Date:  2021-12-29

Review 9.  Antimicrobial Bacillus: Metabolites and Their Mode of Action.

Authors:  Charlie Tran; Ian E Cock; Xiaojing Chen; Yunjiang Feng
Journal:  Antibiotics (Basel)       Date:  2022-01-12
  9 in total

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