Literature DB >> 16806924

Synthesis and pharmacological study of novel pyrido-quinazolone analogues as anti-fungal, antibacterial, and anticancer agents.

Anjani K Tiwari1, A K Mishra, Aruna Bajpai, Pushpa Mishra, R K Sharma, V K Pandey, Vinay Kumar Singh.   

Abstract

A versatile method for novel pyrido-quinazolones was described here and tested for anti-fungal, antibacterial, and anticancerous activities. These synthesized compounds were characterized on the basis of spectroscopic techniques and evaluated for specific radiopharmaceuticals. Preliminary radiolabeling results with (99m)Tc and biological evaluation studies showed promising results for further evaluation in vivo. The efficiency of labeling was more than 98% and complexes were stable for about 18 h at 25 degrees C in the presence of serum.

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Year:  2006        PMID: 16806924     DOI: 10.1016/j.bmcl.2006.06.015

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Synthesis and biological evaluation studies of novel quinazolinone derivatives as antibacterial and anti-inflammatory agents.

Authors:  Mohamed F Zayed; Memy H Hassan
Journal:  Saudi Pharm J       Date:  2013-04-06       Impact factor: 4.330

2.  Synthesis of substituted 3,4-dihydroquinazolinones via a metal free Leuckart-Wallach type reaction.

Authors:  Suvarna Bokale-Shivale; Mohammad A Amin; Rajiv T Sawant; Marc Y Stevens; Lewend Turanli; Adam Hallberg; Suresh B Waghmode; Luke R Odell
Journal:  RSC Adv       Date:  2020-12-23       Impact factor: 3.361

  2 in total

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