Literature DB >> 16805541

Novel and selective palladium-catalyzed annulations of 2-alkynylphenols to form 2-substituted 3-halobenzo[b]furans.

Yun Liang1, Shi Tang, Xu-Dong Zhang, Li-Qiu Mao, Ye-Xiang Xie, Jin-Heng Li.   

Abstract

[reaction: see text] A novel and selective palladium-catalyzed annulation of 2-alkynylphenols method for the synthesis of 2-substituted 3-halobenzo[b]furans is presented. In the presence of PdX(2), CuX(2), and HEt(3)NX, 2-substituted 3-halobenzo[b]furans were selectively obtained as the major products. The mechanism of the reaction was also discussed.

Entities:  

Year:  2006        PMID： 16805541     DOI： 10.1021/ol060908f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Copper-promoted hydration and annulation of 2-fluorophenylacetylene derivatives: from alkynes to benzo[b]furans and benzo[b]thiophenes.

Authors:  Yibiao Li; Liang Cheng; Xiaohang Liu; Bin Li; Ning Sun
Journal:  Beilstein J Org Chem       Date:  2014-12-04       Impact factor: 2.883

2.  Facile synthesis of 2-substituted benzo[b]furans and indoles by copper-catalyzed intramolecular cyclization of 2-alkynyl phenols and tosylanilines.

Authors:  Zhouting Rong; Kexin Gao; Lei Zhou; Jianyuan Lin; Guoying Qian
Journal:  RSC Adv       Date:  2019-06-07       Impact factor: 4.036

3.  Transition-metal-free base catalyzed intramolecular cyclization of 2-ynylphenols for efficient and facile synthesis of 2-substituted benzo[b]furans.

Authors:  Yong Liu; Tao Lu; Wei-Fang Tang; Jian Gao
Journal:  RSC Adv       Date:  2018-08-10       Impact factor: 3.361

4.  One-pot synthesis and property study on thieno[3,2-b]furan compounds.

Authors:  Weimin Ma; Jiawei Huang; Chao Li; Yueren Jiang; Baolin Li; Ting Qi; Xiaozhang Zhu
Journal:  RSC Adv       Date:  2019-03-01       Impact factor: 4.036
  4 in total

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