Literature DB >> 16804905

Structure and function of the components of the human DNA mismatch repair system.

Thomas Jascur1, C Richard Boland.   

Abstract

DNA mismatch repair (MMR) is one of the several enzyme systems involved in DNA homeostasis. DNA MMR is involved in the repair of specific types of errors that occur during new DNA synthesis; loss of this system leads to an accelerated accumulation of potential mutations, and predisposes to certain types of cancers. Germline mutations in some of the DNA MMR genes cause the hereditary cancer predisposition, Lynch syndrome. This review addresses advances in the biochemistry of DNA MMR and its relationship to carcinogenesis.

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Year:  2006        PMID： 16804905     DOI： 10.1002/ijc.22023

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  40 in total

Review 1.  Microsatellite instability in colorectal cancer.

Authors:  C Richard Boland; Ajay Goel
Journal:  Gastroenterology       Date:  2010-06       Impact factor: 22.682

Review 2.  The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside.

Authors:  C Richard Boland; Minoru Koi; Dong K Chang; John M Carethers
Journal:  Fam Cancer       Date:  2007-07-17       Impact factor: 2.375

3.  Recent findings on epigenetic gene abnormalities involved in uterine cancer.

Authors:  Megumi Yanokura; Kouji Banno; Yusuke Kobayashi; Hiroyuki Nomura; Shigenori Hayashi; Eiichiro Tominaga; Daisuke Aoki
Journal:  Mol Clin Oncol       Date:  2017-09-20

4.  Gene expression of the mismatch repair gene MSH2 in primary colorectal cancer.

Authors:  Lars Henrik Jensen; Hidekazu Kuramochi; Dorthe Gylling Crüger; Jan Lindebjerg; Steen Kolvraa; Peter Danenberg; Kathleen Danenberg; Anders Jakobsen
Journal:  Tumour Biol       Date:  2011-07-06

5.  Mismatch repair protein expression in patients with stage II and III sporadic colorectal cancer.

Authors:  Lihua Zhao
Journal:  Oncol Lett       Date:  2018-03-23       Impact factor: 2.967

6.  Molecular signaling mechanisms of apoptosis in hereditary non-polyposis colorectal cancer.

Authors:  Samar Hassen; Nawab Ali; Parimal Chowdhury
Journal:  World J Gastrointest Pathophysiol       Date:  2012-06-15

7.  Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.

Authors:  Yutaka Suehiro; Chi Wai Wong; Lucian R Chirieac; Yutaka Kondo; Lanlan Shen; C Renee Webb; Yee Wai Chan; Annie S Y Chan; Tsun Leung Chan; Tsung-Teh Wu; Asif Rashid; Yuichiro Hamanaka; Yuji Hinoda; Rhonda L Shannon; Xuemei Wang; Jeffrey Morris; Jean-Pierre J Issa; Siu Tsan Yuen; Suet Yi Leung; Stanley R Hamilton
Journal:  Clin Cancer Res       Date:  2008-05-01       Impact factor: 12.531

8.  Stabilization of mismatch repair gene PMS2 by glycogen synthase kinase 3beta is implicated in the treatment of cervical carcinoma.

Authors:  Yuan Zhang; Yi Min Shu; Shu Fang Wang; Bang Hong Da; Ze Hua Wang; Hua Bin Li
Journal:  BMC Cancer       Date:  2010-02-23       Impact factor: 4.430

Review 9.  Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patients.

Authors:  Kristen M Drescher; Poonam Sharma; Henry T Lynch
Journal:  Clin Dev Immunol       Date:  2010-06-10

10.  Clinical significance of epigenetic inactivation of hMLH1 and BRCA1 in Tunisian patients with invasive breast carcinoma.

Authors:  Sondes Karray-Chouayekh; Fatma Trifa; Abdelmajid Khabir; Nouredine Boujelbane; Tahia Sellami-Boudawara; Jamel Daoud; Mounir Frikha; Ali Gargouri; Raja Mokdad-Gargouri
Journal:  J Biomed Biotechnol       Date:  2009-07-29
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