| Literature DB >> 16804572 |
Yongmei Zhao1, Weijiang He, Pengfei Shi, Jianhui Zhu, Lin Qiu, Liping Lin, Zijian Guo.
Abstract
A trinuclear 3N-chelated monofunctional platinum complex, [Pt3(HPTAB)Cl3](ClO4)3 (HPTAB = N,N,N',N',N'',N''-hexakis(2-pyridylmethyl)-1,3,5-tris(aminomethyl)benzene), has been structurally characterized, which binds to DNA and demonstrates much higher potency against the murine leukemia cell line (P-388) and the human nonsmall-cell lung cancer cell line (A-549) than cisplatin.Entities:
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Year: 2006 PMID： 16804572 DOI： 10.1039/b601739h
Source DB: PubMed Journal: Dalton Trans ISSN： 1477-9226 Impact factor: 4.390