Literature DB >> 16804154

Depression and cardiovascular disease: healing the broken-hearted.

Mary A Whooley1.   

Abstract

Major depressive disorder is a risk factor for the development of incident coronary heart disease events in healthy patients and for adverse cardiovascular outcomes in patients with established heart disease. Depression is present in 1 of 5 outpatients with coronary heart disease and in 1 of 3 outpatients with congestive heart failure, yet the majority of cases are not recognized or appropriately treated. It is not known whether treating depression improves cardiovascular outcomes, but antidepressant treatment with selective serotonin reuptake inhibitors is generally safe, alleviates depression, and improves quality of life. This article evaluates the importance of major depression in patients with cardiovascular disease, and provides practical guidance for identifying and treating this disorder.

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Year:  2006        PMID: 16804154      PMCID: PMC2771193          DOI: 10.1001/jama.295.24.2874

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  83 in total

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2.  Major depression is associated with lower omega-3 fatty acid levels in patients with recent acute coronary syndromes.

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Journal:  Biol Psychiatry       Date:  2004-05-01       Impact factor: 13.382

Review 3.  Why is depression bad for the failing heart? A review of the mechanistic relationship between depression and heart failure.

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Review 7.  Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment.

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9.  Relation between depressive symptoms and treadmill exercise capacity in the Heart and Soul Study.

Authors:  Bernice Ruo; John S Rumsfeld; Sharon Pipkin; Mary A Whooley
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  69 in total

1.  Association of anhedonia with recurrent major adverse cardiac events and mortality 1 year after acute coronary syndrome.

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Journal:  Psychoneuroendocrinology       Date:  2007-01-16       Impact factor: 4.905

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Authors:  Sheila Hollins
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Authors:  Susmita Parashar; Viola Vaccarino
Journal:  Curr Treat Options Cardiovasc Med       Date:  2007-08

7.  The impact of medication nonadherence on the relationship between mortality risk and depression in heart failure.

Authors:  Emily C Gathright; Mary A Dolansky; John Gunstad; Joseph D Redle; Richard A Josephson; Shirley M Moore; Joel W Hughes
Journal:  Health Psychol       Date:  2017-07-20       Impact factor: 4.267

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Journal:  Nervenarzt       Date:  2012-11       Impact factor: 1.214

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10.  Membrane omega-3 Fatty Acid deficiency as a preventable risk factor for comorbid coronary heart disease in major depressive disorder.

Authors:  Robert K McNamara
Journal:  Cardiovasc Psychiatry Neurol       Date:  2009-09-16
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