Literature DB >> 16804002

Heat-shock protein 70 genes and human longevity: a view from Denmark.

Ripudaman Singh1, Steen Kølvraa, Peter Bross, Kaare Christensen, Niels Gregersen, Qihua Tan, Uffe Birk Jensen, Hans Eiberg, Suresh I S Rattan.   

Abstract

We have studied the association of three single nucleotide polymorphisms (SNPs) present in the three HSP70 (heat-shock protein) genes on 6p21 with human longevity. The availability of biological samples from various population cohorts in Denmark has given us the opportunity to try novel methods of gene association with human longevity. A significant association of one haplotype with male longevity was observed. Furthermore, a significant difference in the survival of the carriers of the different genotypes in females was observed. We also found an age-dependant decline in the ability of peripheral blood mononuclear cells to respond to heat stress in terms of Hsp70 induction.

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Year:  2006        PMID： 16804002     DOI： 10.1196/annals.1354.040

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  18 in total

1.  Aging does not reduce heat shock protein 70 in the absence of chronic insulin resistance.

Authors:  Kylie Kavanagh; Ashley T Wylie; Tara J Chavanne; Matthew J Jorgensen; V Saroja Voruganti; Anthony G Comuzzie; Jay R Kaplan; Charles E McCall; Stephen B Kritchevsky
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2012-03-08       Impact factor: 6.053

2.  Hormesis-based anti-aging products: a case study of a novel cosmetic.

Authors:  Suresh I S Rattan; Valérie Kryzch; Sylvianne Schnebert; Eric Perrier; Carine Nizard
Journal:  Dose Response       Date:  2012-01-12       Impact factor: 2.658

3.  Genetic polymorphisms of HSP70 in age-related cataract.

Authors:  Yi Zhang; JianYing Gong; Lan Zhang; DaXi Xue; HanRuo Liu; Ping Liu
Journal:  Cell Stress Chaperones       Date:  2013-05-11       Impact factor: 3.667

4.  Anti-inflammatory heat shock protein 70 genes are positively associated with human survival.

Authors:  R Singh; S Kølvraa; P Bross; K Christensen; L Bathum; N Gregersen; Q Tan; S I S Rattan
Journal:  Curr Pharm Des       Date:  2010       Impact factor: 3.116

5.  Reduced heat shock response in human mononuclear cells during aging and its association with polymorphisms in HSP70 genes.

Authors:  Ripudaman Singh; Steen Kølvraa; Peter Bross; Uffe Birk Jensen; Niels Gregersen; Qihua Tan; Christian Knudsen; Suresh I S Rattan
Journal:  Cell Stress Chaperones       Date:  2006       Impact factor: 3.667

6.  HLA complex-linked heat shock protein genes and childhood acute lymphoblastic leukemia susceptibility.

Authors:  Esma Ucisik-Akkaya; Charronne F Davis; Clara Gorodezky; Carmen Alaez; M Tevfik Dorak
Journal:  Cell Stress Chaperones       Date:  2009-12-09       Impact factor: 3.667

7.  Expression of hsp22 and hsp70 transgenes is partially predictive of drosophila survival under normal and stress conditions.

Authors:  Junsheng Yang; John Tower
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2009-05-06       Impact factor: 6.053

8.  Exogenous Hsp70 delays senescence and improves cognitive function in aging mice.

Authors:  Natalia V Bobkova; Mikhail Evgen'ev; David G Garbuz; Alexei M Kulikov; Alexei Morozov; Alexander Samokhin; Dmitri Velmeshev; Natalia Medvinskaya; Inna Nesterova; Andrew Pollock; Evgeny Nudler
Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-14       Impact factor: 11.205

Review 9.  Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.

Authors:  Alexander G Panossian; Thomas Efferth; Alexander N Shikov; Olga N Pozharitskaya; Kenny Kuchta; Pulok K Mukherjee; Subhadip Banerjee; Michael Heinrich; Wanying Wu; De-An Guo; Hildebert Wagner
Journal:  Med Res Rev       Date:  2020-10-25       Impact factor: 12.944

10.  Characterizing binding sites of heat responsive microRNAs and their expression pattern in heat stressed PBMCs of native cattle, exotic cattle and riverine buffaloes.

Authors:  Pallavi Sharma; Ankita Sharma; Monika Sodhi; Preeti Verma; Kumari Parvesh; Shelesh K Swami; Amandeep Jast; Umesh Kumar Shandilya; Manishi Mukesh
Journal:  Mol Biol Rep       Date:  2019-10-22       Impact factor: 2.316
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