BACKGROUND: The origin of moisture in diarrhea feces is unknown but may represent the unabsorbed part of intestinal contents or alternatively, body fluid excreted into the digestive canal. If the latter mechanism contributes to moisture in the feces, active transport of water (H2O) associated with ion exchange channels may be involved. OBJECTIVE: To investigate this possibility we measured the content of moisture and minerals (sodium [Na], potassium [K], calcium [Ca], magnesium [Mg], phosphorus [P], zinc [Zn], iron [Fe], copper [Cu] and manganese [Mn]) in feces collected during a 12-d metabolic study on 11 young Japanese female students. DESIGN: The study was carried out as part of a human mineral balance study. The same quantity of food was supplied to each of the subjects throughout the study without consideration of body weight. Fecal specimens were collected throughout the study and were separated into those originating from the diet during the balance period based on the appearance of the ingested colored marker in the feces. RESULTS: The moisture content of the feces ranged between 53 and 92%. Na content in the feces was low and stable when the moisture content was below 80%, whereas it increased up to serum levels when the moisture content increased above 80%. On the other hand, K content increased when compared to dry matter base. However, when comparing concentration/g moisture, K content increased when moisture was below 70%, but decreased when this rose above 70%.
BACKGROUND: The origin of moisture in diarrhea feces is unknown but may represent the unabsorbed part of intestinal contents or alternatively, body fluid excreted into the digestive canal. If the latter mechanism contributes to moisture in the feces, active transport of water (H2O) associated with ion exchange channels may be involved. OBJECTIVE: To investigate this possibility we measured the content of moisture and minerals (sodium [Na], potassium [K], calcium [Ca], magnesium [Mg], phosphorus [P], zinc [Zn], iron [Fe], copper [Cu] and manganese [Mn]) in feces collected during a 12-d metabolic study on 11 young Japanese female students. DESIGN: The study was carried out as part of a human mineral balance study. The same quantity of food was supplied to each of the subjects throughout the study without consideration of body weight. Fecal specimens were collected throughout the study and were separated into those originating from the diet during the balance period based on the appearance of the ingested colored marker in the feces. RESULTS: The moisture content of the feces ranged between 53 and 92%. Na content in the feces was low and stable when the moisture content was below 80%, whereas it increased up to serum levels when the moisture content increased above 80%. On the other hand, K content increased when compared to dry matter base. However, when comparing concentration/g moisture, K content increased when moisture was below 70%, but decreased when this rose above 70%.
Authors: Rupasri Mandal; Raul Cano; Cindy D Davis; David Hayashi; Scott A Jackson; Christina M Jones; Johanna W Lampe; Marie E Latulippe; Nancy J Lin; Katrice A Lippa; Paulina Piotrowski; Sandra M Da Silva; Kelly S Swanson; David S Wishart Journal: Metabolomics Date: 2020-11-08 Impact factor: 4.290
Authors: Lucas C R Silva; Rodrigo Studart Corrêa; Jamie L Wright; Barbara Bomfim; Lauren Hendricks; Daniel G Gavin; Aleksander Westphal Muniz; Gilvan Coimbra Martins; Antônio Carlos Vargas Motta; Julierme Zimmer Barbosa; Vander de Freitas Melo; Scott D Young; Martin R Broadley; Roberto Ventura Santos Journal: Nat Commun Date: 2021-01-04 Impact factor: 14.919