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Literature DB >> 16800724

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.

Ake Lundwall¹, Vimla Band, Michael Blaber, Judith A Clements, Yves Courty, Eleftherios P Diamandis, Hans Fritz, Hans Lilja, Johan Malm, Lois J Maltais, A Yvonne Olsson, Constantina Petraki, Andreas Scorilas, Georgia Sotiropoulou, Ulf-Håkan Stenman, Carsten Stephan, Maroulio Talieri, George M Yousef.

Abstract

The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1--the tissue kallikrein--and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.

Entities: Disease Gene Species

Mesh：

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Year: 2006 PMID： 16800724 DOI： 10.1515/BC.2006.082

Source DB: PubMed Journal: Biol Chem ISSN： 1431-6730 Impact factor: 3.915

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Cited

26 in total

Review 1. New insights into the functional mechanisms and clinical applications of the kallikrein-related peptidase family.

Authors: Nashmil Emami; Eleftherios P Diamandis
Journal: Mol Oncol Date: 2007-09-15 Impact factor: 6.603

2. Kallikrein cascades in traumatic spinal cord injury: in vitro evidence for roles in axonopathy and neuron degeneration.

Authors: Maja Radulovic; Hyesook Yoon; Nadya Larson; Jianmin Wu; Rachel Linbo; Joshua E Burda; Eleftherios P Diamandis; Sachiko I Blaber; Michael Blaber; Michael G Fehlings; Isobel A Scarisbrick
Journal: J Neuropathol Exp Neurol Date: 2013-11 Impact factor: 3.685

3. Virtual Screening and X-ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 Group.

Authors: Guyan Liang; Xin Chen; Suzanne Aldous; Su-Fen Pu; Shujaath Mehdi; Elaine Powers; Andrew Giovanni; Sathapana Kongsamut; Tianhui Xia; Ying Zhang; Rachel Wang; Zhongli Gao; Gregory Merriman; Larry R McLean; Isabelle Morize
Journal: ACS Med Chem Lett Date: 2012-01-11 Impact factor: 4.345

Review 4. Prostate-specific kallikrein-related peptidases and their relation to prostate cancer biology and detection. Established relevance and emerging roles.

Authors: Daniel L J Thorek; Michael J Evans; Sigrid V Carlsson; David Ulmert; Hans Lilja
Journal: Thromb Haemost Date: 2013-08-01 Impact factor: 5.249

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.

Review 1. New insights into the functional mechanisms and clinical applications of the kallikrein-related peptidase family.

2. Kallikrein cascades in traumatic spinal cord injury: in vitro evidence for roles in axonopathy and neuron degeneration.

3. Virtual Screening and X-ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 Group.

Review 4. Prostate-specific kallikrein-related peptidases and their relation to prostate cancer biology and detection. Established relevance and emerging roles.

5. Kallikrein-5 promotes cleavage of desmoglein-1 and loss of cell-cell cohesion in oral squamous cell carcinoma.

6. Stability of [-2]Pro-PSA in whole blood and serum: analysis for optimal measurement conditions.

7. Impaired male fertility and atrophy of seminiferous tubules caused by haploinsufficiency for Foxa3.

Review 8. Functions of KLK4 and MMP-20 in dental enamel formation.

9. A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15.

10. Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration.