Literature DB >> 16799104

Glucocorticosteroids in football: use and misuse.

J Dvorak1, N Feddermann, K Grimm.   

Abstract

BACKGROUND AND OBJECTIVES: Glucocorticosteroids are widely used in medicine and have shown unchallenged therapeutic potential in several chronic inflammatory and other diseases. They are also widely used in sports medicine for the treatment of conditions such as asthma and acute injuries. In fact, as banned substances, most requests for therapeutic use exemption concern glucocorticosteroids. Nevertheless, their beneficial effect in certain conditions in sports, where inflammation is only a secondary reaction, remains to be validated. This paper aimed to provide a comprehensive review of the literature covering the therapeutic use of glucocorticosteroids since 1977 in conditions ranging from chronic rheumatic illness to peritendinous or intra-articular injection in acute injuries.
METHODS: Search of the medical literature published between 1977 and 2006 using PubMed. Articles relevant to the question "When and if at all is the use of glucocorticosteroids justified in football?" were selected and analysed. RESULTS AND
CONCLUSIONS: The findings clearly point out that, despite the common use of glucocorticosteroids in acute injuries in sports, there is actually limited evidence of the true benefits of such a practice. Physicians must take the possible adverse effects into consideration. In an athlete with clinically verified asthma, inhalational glucocorticosteroids remain first line therapy. Finally, for the purposes of education and prevention of misuse, it should be stressed that a measurable performance enhancing effect of glucocorticoids could not be proved on the basis of the results of the scientific studies to date.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16799104      PMCID: PMC2657490          DOI: 10.1136/bjsm.2006.027599

Source DB:  PubMed          Journal:  Br J Sports Med        ISSN: 0306-3674            Impact factor:   13.800


  60 in total

1.  The role of glucocorticoids in exercise.

Authors:  G D Tharp
Journal:  Med Sci Sports       Date:  1975

2.  Local corticosteroid injection in iliotibial band friction syndrome in runners: a randomised controlled trial.

Authors:  P Gunter; M P Schwellnus
Journal:  Br J Sports Med       Date:  2004-06       Impact factor: 13.800

Review 3.  Glucocorticoid regulation of the inflammatory response to injury.

Authors:  M P Yeager; P M Guyre; A U Munck
Journal:  Acta Anaesthesiol Scand       Date:  2004-08       Impact factor: 2.105

4.  The effects of intratendinous and retrocalcaneal intrabursal injections of corticosteroid on the biomechanical properties of rabbit Achilles tendons.

Authors:  Ronald Hugate; Jason Pennypacker; Marnie Saunders; Paul Juliano
Journal:  J Bone Joint Surg Am       Date:  2004-04       Impact factor: 5.284

Review 5.  Corticosteroids: clinical pharmacology and therapeutic use.

Authors:  S L Swartz; R G Dluhy
Journal:  Drugs       Date:  1978-09       Impact factor: 9.546

6.  [Single treatment with repository steroid in non-articular sport injuries].

Authors:  J J Van Heerden
Journal:  S Afr Med J       Date:  1977-05-14

7.  Septic arthritis following intra-articular steroid injection of the knee--a survey of current practice regarding antiseptic technique used during intra-articular steroid injection of the knee.

Authors:  C P Charalambous; M Tryfonidis; S Sadiq; P Hirst; A Paul
Journal:  Clin Rheumatol       Date:  2003-10-15       Impact factor: 2.980

8.  Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial.

Authors:  Ian Roberts; David Yates; Peter Sandercock; Barbara Farrell; Jonathan Wasserberg; Gabrielle Lomas; Rowland Cottingham; Petr Svoboda; Nigel Brayley; Guy Mazairac; Véronique Laloë; Angeles Muñoz-Sánchez; Miguel Arango; Bennie Hartzenberg; Hussein Khamis; Surakrant Yutthakasemsunt; Edward Komolafe; Fatos Olldashi; Yadram Yadav; Francisco Murillo-Cabezas; Haleema Shakur; Phil Edwards
Journal:  Lancet       Date:  2004 Oct 9-15       Impact factor: 79.321

9.  [Cognitive impairment after accidental high-dose corticosteroid therapy].

Authors:  M Arndt; H J Kunert; H Sass; C Norra
Journal:  Nervenarzt       Date:  2004-09       Impact factor: 1.214

Review 10.  Soft steroids: a new approach to the treatment of inflammatory airways diseases.

Authors:  Maria G Belvisi; David J Hele
Journal:  Pulm Pharmacol Ther       Date:  2003       Impact factor: 3.410

View more
  5 in total

Review 1.  The use of prohibited substances for therapeutic reasons in athletes affected by endocrine diseases and disorders: the therapeutic use exemption (TUE) in clinical endocrinology.

Authors:  L Di Luigi; F Pigozzi; P Sgrò; L Frati; A Di Gianfrancesco; M Cappa
Journal:  J Endocrinol Invest       Date:  2019-11-16       Impact factor: 4.256

2.  Glucocorticoids improve high-intensity exercise performance in humans.

Authors:  Rafael A Casuso; Lars Melskens; Thomas Bruhn; Niels H Secher; Nikolai Baastrup Nordsborg
Journal:  Eur J Appl Physiol       Date:  2013-12-11       Impact factor: 3.078

3.  No variation of physical performance and perceived exertion after adrenal gland stimulation by synthetic ACTH (Synacthen) in cyclists.

Authors:  Norbert Baume; Graeme Steel; Tony Edwards; Eric Thorstensen; Benjamin F Miller
Journal:  Eur J Appl Physiol       Date:  2008-06-27       Impact factor: 3.078

4.  The use of medication and nutritional supplements during FIFA World Cups 2002 and 2006.

Authors:  P Tscholl; A Junge; J Dvorak
Journal:  Br J Sports Med       Date:  2008-02-28       Impact factor: 13.800

5.  How the Iranian Football Coaches and Players Know About Doping?

Authors:  Tohid Seif Barghi; Farzin Halabchi; Jiri Dvorak; Heydar Hosseinnejad
Journal:  Asian J Sports Med       Date:  2015-06-20
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.