Yuan-Chi Lin1, Brenda Golianu. 1. Department of Anesthesia, Children's Hospital Boston; Harvard Medical School, Boston, MA 02115, USA. yuan-chi.lin@tch.harvard.edu
Abstract
STUDY OBJECTIVE: To review anesthesia and pain management in pediatric patients with recessive dystrophic epidermolysis bullosa (RDEB). STUDY DESIGN: Retrospective study. SETTING: University-affiliated pediatric hospital. PATIENTS: 25 pediatric patients with RDEB had a total of 121 surgical procedures. MEASUREMENTS AND MAIN RESULTS: Pediatric patients with RDEB could have vesicles and bullae formation in the skin in response to trauma, friction, or pressure. The common surgical procedures for patients with RDEB were balloon dilation of esophageal strictures (38%), pseudosyndactyly release with or without skin graft (27%), postsurgical or skin care related dressing changes (21%), percutaneous endoscopic gastrostomy tube placement (8%), and circumcision (2%). Our anesthetic techniques included general inhalational anesthesia using mask (21%), general anesthesia using endotracheal tube (48%), and intravenous sedation (31%). No death or other major perioperative anesthetic complications occurred in these reported cases. CONCLUSIONS: Patients with RDEB can present considerable management issues for the anesthesiologists. Anesthesia and pain management can be carefully delivered with proper preoperative evaluation and preparation for pediatric patients with RDEB.
STUDY OBJECTIVE: To review anesthesia and pain management in pediatric patients with recessive dystrophic epidermolysis bullosa (RDEB). STUDY DESIGN: Retrospective study. SETTING: University-affiliated pediatric hospital. PATIENTS: 25 pediatric patients with RDEB had a total of 121 surgical procedures. MEASUREMENTS AND MAIN RESULTS: Pediatric patients with RDEB could have vesicles and bullae formation in the skin in response to trauma, friction, or pressure. The common surgical procedures for patients with RDEB were balloon dilation of esophageal strictures (38%), pseudosyndactyly release with or without skin graft (27%), postsurgical or skin care related dressing changes (21%), percutaneous endoscopic gastrostomy tube placement (8%), and circumcision (2%). Our anesthetic techniques included general inhalational anesthesia using mask (21%), general anesthesia using endotracheal tube (48%), and intravenous sedation (31%). No death or other major perioperative anesthetic complications occurred in these reported cases. CONCLUSIONS:Patients with RDEB can present considerable management issues for the anesthesiologists. Anesthesia and pain management can be carefully delivered with proper preoperative evaluation and preparation for pediatric patients with RDEB.
Authors: Wolfgang Stehr; Michael K Farrell; Anne W Lucky; Neil D Johnson; John M Racadio; Richard G Azizkhan Journal: Pediatr Surg Int Date: 2007-12-20 Impact factor: 1.827
Authors: Susanne Krämer; James Lucas; Francisca Gamboa; Miguel Peñarrocha Diago; David Peñarrocha Oltra; Marcelo Guzmán-Letelier; Sanchit Paul; Gustavo Molina; Lorena Sepúlveda; Ignacio Araya; Rubén Soto; Carolina Arriagada; Anne W Lucky; Jemima E Mellerio; Roger Cornwall; Fatimah Alsayer; Reinhard Schilke; Mark Adam Antal; Fernanda Castrillón; Camila Paredes; Maria Concepción Serrano; Victoria Clark Journal: Spec Care Dentist Date: 2020-11