Literature DB >> 16797108

[Cytomegalovirus myelitis in immunocompetent adult].

N Ben Abdelhafidh1, R Battikh, J Laabidi, F M'sadek, F Ajili, M Ben Moussa, A Amor, N Ben Abdallah, B Louzir, S Othmani.   

Abstract

INTRODUCTION: Cytomegalovirus (CMV) infection occurs in 40 to 100% of general population. It is often asymptomatic in immunocompetent subject but may induce neurological syndromes such as encephalitis and myelitis. CASE RECORD: We reported a case of a 64-years-old woman immunocompetent, with acute proximal upper and lower limb weakness, paresthesias and two episodes of urinary retention. MRI of the spine showed abnormal enhancement from cervical to lumbar spine indicative for myelitis. Diagnosis of CMV associated myelitis was confirmed by a positive CMV serology. Administration of ganciclovir was followed by a partial improvement in five months. DISCUSSION: Few cases of CMV acute myelitis in immunocompetent patients have been reported in the literature. The pathogenesis is not well known, however, immune-mediated central nervous system damage may be attributed to the pathogenesis of the disease. Early diagnosis and treatment improves the prognosis.

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Year:  2006        PMID: 16797108     DOI: 10.1016/j.revmed.2006.04.020

Source DB:  PubMed          Journal:  Rev Med Interne        ISSN: 0248-8663            Impact factor:   0.728


  3 in total

1.  Extensive longitudinal myelitis due to cytomegalovirus infection.

Authors:  Rihab Ben Dhia; Mouna Aissi; Mariem Mhiri; Mahbouba Frih Ayed
Journal:  J Neurovirol       Date:  2021-08-27       Impact factor: 2.643

2.  Cytomegalovirus associated transverse myelitis in an immunocompetent host with DNA detection in cerebrospinal fluid; a case report.

Authors:  Suneth Karunarathne; Dumitha Govindapala; Yapa Udayakumara; Harshini Fernando
Journal:  BMC Res Notes       Date:  2012-07-20

3.  Cytomegalovirus-associated encephalomyelitis in an immunocompetent adult: a two-stage attack of direct viral and delayed immune-mediated invasions. case report.

Authors:  Kensuke Daida; Yuta Ishiguro; Hiroto Eguchi; Yutaka Machida; Nobutaka Hattori; Hideto Miwa
Journal:  BMC Neurol       Date:  2016-11-17       Impact factor: 2.474

  3 in total

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