Literature DB >> 16794340

Repression of secondary metabolite production by exogenous cAMP in Monascus.

Tsuyoshi Miyake1, Ming-Yong Zhang, Isato Kono, Nobuyuki Nozaki, Hiroyuki Sammoto.   

Abstract

The cAMP signal pathway controls various biological functions, including secondary metabolism of filamentous fungi. We found that exogenous cAMP represses the production of lovastatin, red pigments, and citrinin in Monascus. Interestingly, a mutant MK-1 with increased lovastatin and red pigments production was not influenced by cAMP on these productions, indicating that cAMP signaling might be lacking in MK-1.

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Year:  2006        PMID: 16794340     DOI: 10.1271/bbb.50686

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  6 in total

1.  Red pigment production by Penicillium purpurogenum GH2 is influenced by pH and temperature.

Authors:  Alejandro Méndez; Catalina Pérez; Julio Cesar Montañéz; Gabriela Martínez; Cristóbal Noé Aguilar
Journal:  J Zhejiang Univ Sci B       Date:  2011-12       Impact factor: 3.066

Review 2.  Monascus secondary metabolites: production and biological activity.

Authors:  Petra Patakova
Journal:  J Ind Microbiol Biotechnol       Date:  2012-11-20       Impact factor: 3.346

3.  Induction of apoptosis and ganoderic acid biosynthesis by cAMP signaling in Ganoderma lucidum.

Authors:  Bang-Jau You; Ni Tien; Miin-Huey Lee; Bo-Ying Bao; Yih-Shyuan Wu; Tsung-Chi Hu; Hong-Zin Lee
Journal:  Sci Rep       Date:  2017-03-23       Impact factor: 4.379

4.  Insights into the Underlying Mechanism of Ochratoxin A Production in Aspergillus niger CBS 513.88 Using Different Carbon Sources.

Authors:  Shan Wei; Chaojiang Hu; Ping Nie; Huanchen Zhai; Shuaibing Zhang; Na Li; Yangyong Lv; Yuansen Hu
Journal:  Toxins (Basel)       Date:  2022-08-12       Impact factor: 5.075

5.  Does the second messenger cAMP have a more complex role in controlling filamentous fungal morphology and metabolite production?

Authors:  Ramkumar B Nair; Rebecca Gmoser; Patrik R Lennartsson; Mohammad J Taherzadeh
Journal:  Microbiologyopen       Date:  2018-04-06       Impact factor: 3.139

6.  The Effect of Blue Light on the Production of Citrinin in Monascus purpureus M9 by Regulating the mraox Gene through lncRNA AOANCR.

Authors:  Hua Yang; Xufeng Wang; Zhenjing Li; Qingbin Guo; Mingguan Yang; Di Chen; Changlu Wang
Journal:  Toxins (Basel)       Date:  2019-09-13       Impact factor: 4.546

  6 in total

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