Literature DB >> 16793175

Carrier-mediated delivery of peptidic drugs for cancer therapy.

Crispin R Dass1, Peter F M Choong.   

Abstract

Protein and peptide drugs are used for treatment of a variety of ailments. However, their wider use has been hindered by issues such as poor bioavailability in vivo and the cost involved in producing these drugs. This review discusses the various carrier-mediated methods used for delivery of peptide and protein drugs, with emphasis on liposomal and microspherical drug delivery systems. A brief look at the types of peptidic drugs currently in use clinically, and a brief discourse on several novel ideas for better protein delivery systems for cancer therapy is included.

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Year:  2006        PMID: 16793175     DOI: 10.1016/j.peptides.2006.05.020

Source DB:  PubMed          Journal:  Peptides        ISSN: 0196-9781            Impact factor:   3.750


  5 in total

1.  Archaeosome: as new drug carrier for delivery of Paclitaxel to breast cancer.

Authors:  Seyed Ebrahim Alavi; Hamidreza Mansouri; Maedeh Koohi Moftakhari Esfahani; Fatemeh Movahedi; Azim Akbarzadeh; Mohsen Chiani
Journal:  Indian J Clin Biochem       Date:  2013-02-12

2.  Study of toxicity effect of pegylated nanoliposomal artemisinin on breast cancer cell line.

Authors:  Neda Dadgar; Seyed Ebrahim Alavi; Maedeh Koohi Moftakhari Esfahani; Azim Akbarzadeh
Journal:  Indian J Clin Biochem       Date:  2013-02-10

3.  Preparation and Characterization of Stealth Archaeosomes Based on a Synthetic PEGylated Archaeal Tetraether Lipid.

Authors:  Julie Barbeau; Sandrine Cammas-Marion; Pierrick Auvray; Thierry Benvegnu
Journal:  J Drug Deliv       Date:  2011-03-21

4.  Intracellular calcium is a target of modulation of apoptosis in MCF-7 cells in the presence of IgA adsorbed to polyethylene glycol.

Authors:  Adenilda Cristina Honorio-França; Gabriel Triches Nunes; Danny Laura Gomes Fagundes; Patrícia Gelli Feres de Marchi; Rubian Trindade da Silva Fernandes; Juliana Luzia França; Aline do Carmo França-Botelho; Lucélia Campelo Albuquerque Moraes; Fernando de Pilla Varotti; Eduardo Luzía França
Journal:  Onco Targets Ther       Date:  2016-02-03       Impact factor: 4.147

5.  Directed regioselective ortho,ortho'-magnesiations of aromatics and heterocycles using sBu2Mg in toluene.

Authors:  Andreas Hess; Jan P Prohaska; Sabrina B Doerrich; Florian Trauner; Ferdinand H Lutter; Sébastien Lemaire; Simon Wagschal; Konstantin Karaghiosoff; Paul Knochel
Journal:  Chem Sci       Date:  2021-05-18       Impact factor: 9.825

  5 in total

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