Literature DB >> 16791316

Inotilone and related phenylpropanoid polyketides from Inonotus sp. and their identification as potent COX and XO inhibitors.

Hilaire V Kemami Wangun1, Albert Härtl, Trinh Tam Kiet, Christian Hertweck.   

Abstract

By bioassay-guided isolation, phenylpropanoid-derived polyketides, including an unusual 5-methyl-3(2H)-furanone derivative (inotilone) with potent cyclooxygenase (COX) and xanthone oxidase (XO) inhibitory activities were obtained from the fruiting body of the mushroom Inonotus sp.

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Year:  2006        PMID： 16791316     DOI： 10.1039/b604505g

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  5 in total

1.  Biological activities of two polypore macrofungi (Basidiomycota) and characterization of their compounds using HPLC-DAD and LC-ESI-MS/MS.

Authors:  Samaneh Chaharmiri Dokhaharani; Masoomeh Ghobad-Nejhad; Hamid Moghimi; Abbas Farazmand; Hossein Rahmani
Journal:  Folia Microbiol (Praha)       Date:  2021-06-13       Impact factor: 2.099

Review 2.  Therapeutic Potential of Hispidin-Fungal and Plant Polyketide.

Authors:  Kseniia A Palkina; Daria A Ipatova; Ekaterina S Shakhova; Anastasia V Balakireva; Nadezhda M Markina
Journal:  J Fungi (Basel)       Date:  2021-04-22

3.  Aethiopinolones A-E, New Pregnenolone Type Steroids from the East African Basidiomycete Fomitiporia aethiopica.

Authors:  Clara Chepkirui; Winnie C Sum; Tian Cheng; Josphat C Matasyoh; Cony Decock; Marc Stadler
Journal:  Molecules       Date:  2018-02-09       Impact factor: 4.411

4.  Whole-genome sequence of Phellinus gilvus (mulberry Sanghuang) reveals its unique medicinal values.

Authors:  Jinxi Huo; Shi Zhong; Xin Du; Yinglong Cao; Wenqiong Wang; Yuqing Sun; Yu Tian; Jianxun Zhu; Jine Chen; Lijiang Xuan; Chongming Wu; Yougui Li
Journal:  J Adv Res       Date:  2020-04-28       Impact factor: 10.479

Review 5.  Diverse Metabolites and Pharmacological Effects from the Basidiomycetes Inonotus hispidus.

Authors:  Zhenxin Wang; Xilong Feng; Chengwei Liu; Jinming Gao; Jianzhao Qi
Journal:  Antibiotics (Basel)       Date:  2022-08-12
  5 in total

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