Literature DB >> 16790912

Back to the future: the history and development of the clinical linear accelerator.

David I Thwaites1, John B Tuohy.   

Abstract

The linear accelerator (linac) is the accepted workhorse in radiotherapy in 2006. The first medical linac treated its first patient, in London, in 1953, so the use of these machines in clinical practice has been almost co-existent with the lifetime of Physics in Medicine and Biology. This review is a personal selection of things the authors feel are interesting in the history, particularly the early history, and development of clinical linacs. A brief look into the future is also given. One significant theme throughout is the continuity of ideas, building on previous experience. We hope the review might re-connect younger radiotherapy physicists in particular with some of the history and emphasize the continual need, in any human activity, to remain aware of the past, in order to make best use of past experience when taking decisions in the present.

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Year:  2006        PMID: 16790912     DOI: 10.1088/0031-9155/51/13/R20

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  8 in total

Review 1.  Volumetric modulated arc therapy: a review of current literature and clinical use in practice.

Authors:  M Teoh; C H Clark; K Wood; S Whitaker; A Nisbet
Journal:  Br J Radiol       Date:  2011-11       Impact factor: 3.039

Review 2.  Optimizing tumor immune response through combination of radiation and immunotherapy.

Authors:  Alissar El Chediak; Ali Shamseddine; Larry Bodgi; Jean-Pierre Obeid; Fady Geara; Youssef H Zeidan
Journal:  Med Oncol       Date:  2017-08-21       Impact factor: 3.064

3.  Automatic generation of three-dimensional dose reconstruction data for two-dimensional radiotherapy plans for historically treated patients.

Authors:  Ziyuan Wang; Marco Virgolin; Peter A N Bosman; Koen F Crama; Brian V Balgobind; Arjan Bel; Tanja Alderliesten
Journal:  J Med Imaging (Bellingham)       Date:  2020-02-03

4.  Guided post-acceleration of laser-driven ions by a miniature modular structure.

Authors:  Satyabrata Kar; Hamad Ahmed; Rajendra Prasad; Mirela Cerchez; Stephanie Brauckmann; Bastian Aurand; Giada Cantono; Prokopis Hadjisolomou; Ciaran L S Lewis; Andrea Macchi; Gagik Nersisyan; Alexander P L Robinson; Anna M Schroer; Marco Swantusch; Matt Zepf; Oswald Willi; Marco Borghesi
Journal:  Nat Commun       Date:  2016-04-18       Impact factor: 14.919

5.  Monte Carlo Investigation of Photon Beam Characteristics and its Variation with Incident Electron Beam Parameters for Indigenous Medical Linear Accelerator.

Authors:  Subhalaxmi Mishra; P K Dixit; T Palani Selvam; Sanket S Yavalkar; D D Deshpande
Journal:  J Med Phys       Date:  2018 Jan-Mar

6.  Comparison of Dosimetric Gains Provided by Intensity-Modulated Radiotherapy, Volume-Modulated Arc Therapy, and Helical Tomotherapy for High-Grade Glioma.

Authors:  Pei Liu; Gui Liu; Guihua Wang; Weibing Zhou; Yangqing Sun; Wen Chen; Qian Zeng; Jidong Hong; Qiongxuan Xie; Ludi Ou; Rui Wei
Journal:  Biomed Res Int       Date:  2020-03-18       Impact factor: 3.411

7.  IR-Surviving NSCLC Cells Exhibit Different Patterns of Molecular and Cellular Reactions Relating to the Multifraction Irradiation Regimen and p53-Family Proteins Expression.

Authors:  Lina Alhaddad; Margarita Pustovalova; Taisia Blokhina; Roman Chuprov-Netochin; Andreyan N Osipov; Sergey Leonov
Journal:  Cancers (Basel)       Date:  2021-05-28       Impact factor: 6.639

8.  Dosimetric comparisons of craniospinal axis irradiation using helical tomotherapy, volume-modulated arc therapy and intensity-modulated radiotherapy for medulloblastoma.

Authors:  Yangqing Sun; Gui Liu; Wen Chen; Taili Chen; Pei Liu; Qian Zeng; Jidong Hong; Rui Wei
Journal:  Transl Cancer Res       Date:  2019-02       Impact factor: 1.241

  8 in total

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