Literature DB >> 16790607

A double-blind, randomized controlled trial on the use of a 50:50 mixture of nitrous oxide/oxygen in pain relief during suction evacuation for the first trimester pregnancy termination.

Anita Sik Yau Kan1, Natalie Caves, Sylvia Yuen Wai Wong, Ernest Hung Yu Ng, Pak Chung Ho.   

Abstract

BACKGROUND: This prospective study assessed the role of a 50:50 mixture of nitrous oxide (N2O) and oxygen for pain relief during the termination of first trimester pregnancies by suction evacuation under conscious sedation.
METHODS: Ninety women undergoing suction evacuation up to 12 weeks of gestation were randomized by a computer-generated randomization list and allocated using sealed envelopes to receive the N2O/O2 mixture or air during the operation. Pain scores during and after suction evacuation, post-operative side effects and satisfaction level were compared.
RESULTS: No statistically significant differences in pain scores, post-operative side effects and satisfaction levels were found between the two groups.
CONCLUSION: N2O/O2 did not reduce the pain level during suction evacuation for the first trimester pregnancy termination under conscious sedation.

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Year:  2006        PMID: 16790607     DOI: 10.1093/humrep/del234

Source DB:  PubMed          Journal:  Hum Reprod        ISSN: 0268-1161            Impact factor:   6.918


  5 in total

1.  Nitrous oxide versus oral sedation for pain management of first-trimester surgical abortion - a randomized study.

Authors:  Rameet H Singh; Maria Montoya; Eve Espey; Lawrence Leeman
Journal:  Contraception       Date:  2017-06-16       Impact factor: 3.375

2.  Nitrous oxide for pain management of first trimester surgical abortion -- a randomized controlled pilot study.

Authors:  Rameet H Singh; Eve Espey; Shannon Carr; Brenda Pereda; Tony Ogburn; Lawrence Leeman
Journal:  Contraception       Date:  2014-10-22       Impact factor: 3.375

3.  Analgesic efficacy and safety of paracervical block versus conscious sedation in the surgical evacuation of the uterus following first-trimester incomplete miscarriages: A randomised controlled trial.

Authors:  Nnenna A Nweke; Chidebe Christian Anikwe; Richard L Ewah; Osita S Umeononihu; Justus N Eze
Journal:  SAGE Open Med       Date:  2022-07-24

4.  Comparison of remifentanil: Entonox with Entonox alone in labor analgesia.

Authors:  Mojtaba Rahimi Varposhti; Naghmeh Ahmadi; Mehrdad Masoodifar; Zahra Shahshahan; Morteza Heydari Tabatabaie
Journal:  Adv Biomed Res       Date:  2013-11-30

5.  Risk Assessment of Using Entonox for the Relief of Labor Pain: A Healthcare Failure Modes and Effects Analysis Approach.

Authors:  Tahereh Fathi Najafi; Narjes Bahri; Hosein Ebrahimipour; Ali Vafaee Najar; Yasamin Molavi Taleghani
Journal:  Electron Physician       Date:  2016-03-25
  5 in total

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