Literature DB >> 16790393

Bioinformatics and cancer: an essential alliance.

Joaquín Dopazo1.   

Abstract

Modern research in cancer has been revolutionized by the introduction of new high-throughput methodologies such as DNA microarrays. Keeping the pace with these technologies, the bioinformatics offer new solutions for data analysis and, what is more important, it permits to formulate a new class of hypothesis inspired in systems biology, more oriented to blocks of functionally-related genes. Although software implementations for this new methodologies is new there are some options already available. Bioinformatic solutions for other high-throughput techniques such as array-CGH of large-scale genotyping is also revised.

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Year:  2006        PMID: 16790393     DOI: 10.1007/s12094-006-0194-6

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  75 in total

Review 1.  Beyond Mendel: an evolving view of human genetic disease transmission.

Authors:  Jose L Badano; Nicholas Katsanis
Journal:  Nat Rev Genet       Date:  2002-10       Impact factor: 53.242

Review 2.  Comparison and meta-analysis of microarray data: from the bench to the computer desk.

Authors:  Yves Moreau; Stein Aerts; Bart De Moor; Bart De Strooper; Michal Dabrowski
Journal:  Trends Genet       Date:  2003-10       Impact factor: 11.639

3.  A vision for the future of genomics research.

Authors:  Francis S Collins; Eric D Green; Alan E Guttmacher; Mark S Guyer
Journal:  Nature       Date:  2003-04-14       Impact factor: 49.962

4.  PupaSNP Finder: a web tool for finding SNPs with putative effect at transcriptional level.

Authors:  Lucía Conde; Juan M Vaquerizas; Javier Santoyo; Fátima Al-Shahrour; Sergio Ruiz-Llorente; Mercedes Robledo; Joaquín Dopazo
Journal:  Nucleic Acids Res       Date:  2004-07-01       Impact factor: 16.971

Review 5.  Mapping complex disease loci in whole-genome association studies.

Authors:  Christopher S Carlson; Michael A Eberle; Leonid Kruglyak; Deborah A Nickerson
Journal:  Nature       Date:  2004-05-27       Impact factor: 49.962

6.  The future of association studies: gene-based analysis and replication.

Authors:  Benjamin M Neale; Pak C Sham
Journal:  Am J Hum Genet       Date:  2004-07-22       Impact factor: 11.025

7.  Systems biology and new technologies enable predictive and preventative medicine.

Authors:  Leroy Hood; James R Heath; Michael E Phelps; Biaoyang Lin
Journal:  Science       Date:  2004-10-22       Impact factor: 47.728

8.  Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Authors:  Aravind Subramanian; Pablo Tamayo; Vamsi K Mootha; Sayan Mukherjee; Benjamin L Ebert; Michael A Gillette; Amanda Paulovich; Scott L Pomeroy; Todd R Golub; Eric S Lander; Jill P Mesirov
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-30       Impact factor: 11.205

9.  BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data.

Authors:  Lao H Saal; Carl Troein; Johan Vallon-Christersson; Sofia Gruvberger; Ake Borg; Carsten Peterson
Journal:  Genome Biol       Date:  2002-07-15       Impact factor: 13.583

10.  BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments.

Authors:  Fátima Al-Shahrour; Pablo Minguez; Juan M Vaquerizas; Lucía Conde; Joaquín Dopazo
Journal:  Nucleic Acids Res       Date:  2005-07-01       Impact factor: 16.971

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  3 in total

1.  Developing effective tumor vaccines: basis, challenges and perspectives.

Authors:  Qingwen Xu; Weifeng Chen
Journal:  Front Med China       Date:  2007-02-01

2.  AMMO-Prot: amine system project 3D-model finder.

Authors:  Ismael Navas-Delgado; Raúl Montañez; Almudena Pino-Angeles; Aurelio A Moya-García; José Luis Urdiales; Francisca Sánchez-Jiménez; José F Aldana-Montes
Journal:  BMC Bioinformatics       Date:  2008-04-25       Impact factor: 3.169

3.  Bioinformatics Analysis of the Molecular Mechanism and Potential Treatment Target of Ankylosing Spondylitis.

Authors:  Fanyan Meng; Ningna Du; Daoming Xu; Li Kuai; Lanying Liu; Minning Xiu
Journal:  Comput Math Methods Med       Date:  2021-07-21       Impact factor: 2.238

  3 in total

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