| Literature DB >> 1679015 |
P Rogue1, A Hanauer, J Zwiller, A N Malviya, G Vincendon.
Abstract
The effect of prolonged administration of antagonists on rat striatal dopamine D2 receptor binding and mRNA content was examined. Both haloperidol (2 and 4 mg/kg) and sulpiride (10 mg/kg) induced a significant rise in total D2 and D2(444) mRNA level and in Bmax. Regulation of messenger RNA accumulation is thus an important determinant of dopamine D2 receptor density.Entities:
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Year: 1991 PMID： 1679015 DOI： 10.1016/0922-4106(91)90092-v
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432