Literature DB >> 16789119

Characterization of deoxyribonucleases induced by poxviruses.

C Jungwirth1, J Launer, G Dombrowski, I Horák.   

Abstract

Increases in deoxyribonuclease activity assayed at alkaline pH can be observed in poxvirus-infected cells when native or denatured deoxyribonucleic acid (DNA) is used as substrate. The deoxyribonuclease assayable with native DNA as substrate, induced in HeLa cells by cowpoxvirus or vaccinia virus WR, can be separated from the corresponding enzyme present in normal cells by chromatography on diethylaminoethyl cellulose. In addition, the two enzymes induced in the virus-infected cells differ from each other in their chromatographic properties. The two induced enzymes have been further characterized with respect to properties of enzymatic reaction.

Entities:  

Year:  1969        PMID: 16789119      PMCID: PMC375950     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  12 in total

1.  MESSENGER RNA IN CELLS INFECTED WITH VACCINIA VIRUS.

Authors:  Y BECKER; W K JOKLIK
Journal:  Proc Natl Acad Sci U S A       Date:  1964-04       Impact factor: 11.205

2.  The purification fo four strains of poxvirus.

Authors:  W K JOKLIK
Journal:  Virology       Date:  1962-09       Impact factor: 3.616

3.  Factors involved in the initiation of multiplication of vaccinia virus.

Authors:  H HANAFUSA
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1962

4.  A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.

Authors:  K BURTON
Journal:  Biochem J       Date:  1956-02       Impact factor: 3.857

5.  Regulation of virus-induced deoxyribonucleases.

Authors:  B R McAuslan; J R Kates
Journal:  Proc Natl Acad Sci U S A       Date:  1966-06       Impact factor: 11.205

6.  A new DNA-exonuclease in cells infected with herpes virus: partial purification and properties of the enzyme.

Authors:  J M Morrison; H M Keir
Journal:  J Gen Virol       Date:  1968-12       Impact factor: 3.891

7.  The use of gel filtration to distinguish between endonucleolytic and exonucleolytic types of degradation.

Authors:  H Birnboim
Journal:  Biochim Biophys Acta       Date:  1966-04-18

8.  Studies on "early" enzymes in HeLa cells infected with vaccinia virus.

Authors:  C Jungwirth; W K Joklik
Journal:  Virology       Date:  1965-09       Impact factor: 3.616

9.  The nature of poxvirus-induced deoxyribonucleas.

Authors:  L J Eron; B R McAuslan
Journal:  Biochem Biophys Res Commun       Date:  1966-03-08       Impact factor: 3.575

10.  Nucleases of virus-infected animal cells.

Authors:  B R McAuslan; P Herde; D Pett; J Ross
Journal:  Biochem Biophys Res Commun       Date:  1965-09-08       Impact factor: 3.575

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  2 in total

1.  Breakdown of HeLa cell DNA mediated by vaccinia virus.

Authors:  J R Parkhurst; A R Peterson; C Heidelberger
Journal:  Proc Natl Acad Sci U S A       Date:  1973-11       Impact factor: 11.205

2.  Fibroma virus-induced acid deoxyribonuclease in rabbit kidney cells.

Authors:  S P Sahu; H C Minocha
Journal:  Arch Gesamte Virusforsch       Date:  1974
  2 in total

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