Literature DB >> 16788220

Status epilepticus caused by a myxoedema coma.

H J Jansen1, S R Oedit Doebé, E S Louwerse, J C van der Linden, P M Netten.   

Abstract

The case of a 63-year-old woman who presented with status epilepticus, coma and hypoventilation is reported. A primary neurological cause was considered. Hypothermia led to further investigations and a diagnosis of severe hypothyroidism. The neurological complications of hyperthyriodism include alteration in mental status with slowness, decreased concentration and lethargy, headache, cranial nerve palsies, dysarthria, hoarseness, myopathy, neuropathy, reflex changes, ataxia, and psychotic episodes. Our patient suffered from a rare consequence of severe hypothyroidism presenting with status epilepticus and she died despite treatment. To our knowledge this is the second patient to be reported with myxoedema coma with this kind of presentation. Despite therapeutic options, there is a high mortality rate.

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Year:  2006        PMID: 16788220

Source DB:  PubMed          Journal:  Neth J Med        ISSN: 0300-2977            Impact factor:   1.422


  5 in total

Review 1.  Thyroid emergencies.

Authors:  Joanna Klubo-Gwiezdzinska; Leonard Wartofsky
Journal:  Med Clin North Am       Date:  2012-02-17       Impact factor: 5.456

2.  Nonconvulsive status epilepticus induced by acute hypothyroidism in a critically ill patient.

Authors:  Monica Rocco; Stefano Pro; Elisa Alessandri; Edoardo Vicenzini; Oriano Mecarelli
Journal:  Intensive Care Med       Date:  2010-12-17       Impact factor: 17.440

Review 3.  Endocrine Emergencies With Neurologic Manifestations.

Authors:  Makoto Ishii
Journal:  Continuum (Minneap Minn)       Date:  2017-06

4.  Reactions of the immune system in epilepsy.

Authors:  Inimioara Mihaela Cojocaru; Manole Cojocaru
Journal:  Maedica (Buchar)       Date:  2010-07

5.  Complete recovery after severe myxoedema coma complicated by status epilepticus.

Authors:  Jesper Fjølner; Esben Søndergaard; Ulla Kampmann; Søren Nielsen
Journal:  BMJ Case Rep       Date:  2015-03-25
  5 in total

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