Literature DB >> 16786237

Differential diagnosis and management of acute profound thrombocytopenia by tirofiban: a case report.

Burcu Demirkan1, Yesim Guray, Umit Guray, Sule Korkmaz.   

Abstract

Although the glycoprotein IIb/IIIa receptor inhibitors have improved outcomes of patients with acute coronary syndrome (ACS), therapy with these agents may cause thrombocytopenia with bleeding complications. This adverse effect is seemed to be rare with tirofiban. In this report, we describe a case of acute profound thrombocytopenia within two hours of tirofiban administration and review the differential diagnosis and the management of thrombocytopenia.

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Year:  2006        PMID: 16786237     DOI: 10.1007/s11239-006-7789-1

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  12 in total

1.  Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. The RESTORE Investigators. Randomized Efficacy Study of Tirofiban for Outcomes and REstenosis.

Authors: 
Journal:  Circulation       Date:  1997-09-02       Impact factor: 29.690

2.  Temporal aspects of heparin-induced thrombocytopenia.

Authors:  T E Warkentin; J G Kelton
Journal:  N Engl J Med       Date:  2001-04-26       Impact factor: 91.245

Review 3.  A practical approach to the diagnosis and management of thrombocytopenia associated with glycoprotein IIb/IIIa receptor inhibitors.

Authors:  J Llevadot; S A Coulter; R P Giugliano
Journal:  J Thromb Thrombolysis       Date:  2000-02       Impact factor: 2.300

4.  A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina.

Authors: 
Journal:  N Engl J Med       Date:  1998-05-21       Impact factor: 91.245

5.  Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction.

Authors: 
Journal:  N Engl J Med       Date:  1998-05-21       Impact factor: 91.245

6.  Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa.

Authors:  B Bednar; J J Cook; M A Holahan; M E Cunningham; P A Jumes; R A Bednar; G D Hartman; R J Gould
Journal:  Blood       Date:  1999-07-15       Impact factor: 22.113

7.  Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials.

Authors:  Eric Boersma; Robert A Harrington; David J Moliterno; Harvey White; Pierre Théroux; Frans Van de Werf; Anneke de Torbal; Paul W Armstrong; Lars C Wallentin; Robert G Wilcox; John Simes; Robert M Califf; Eric J Topol; Maarten L Simoons
Journal:  Lancet       Date:  2002-01-19       Impact factor: 79.321

8.  Intravenous glycoprotein IIb/IIIa receptor antagonists reduce mortality after percutaneous coronary interventions.

Authors:  Evangelia Karvouni; Demosthenes G Katritsis; John P A Ioannidis
Journal:  J Am Coll Cardiol       Date:  2003-01-01       Impact factor: 24.094

9.  Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa.

Authors:  Daniel W Bougie; Peter R Wilker; Elizabeth D Wuitschick; Brian R Curtis; Mohammad Malik; Stewart Levine; Richard N Lind; Jaime Pereira; Richard H Aster
Journal:  Blood       Date:  2002-09-15       Impact factor: 22.113

Review 10.  Platelet-endothelial interactions: sepsis, HIT, and antiphospholipid syndrome.

Authors:  Theodore E Warkentin; William C Aird; Jacob H Rand
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2003
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  2 in total

1.  Vanishing platelets: rapid and extreme tirofiban-induced thrombocytopenia after percutaneous coronary intervention for acute myocardial infarction.

Authors:  Nasir Rahman; Fahim H Jafary
Journal:  Tex Heart Inst J       Date:  2010

Review 2.  Severe thrombocytopenia and alveolar hemorrhage represent two types of bleeding tendency during tirofiban treatment: case report and literature review.

Authors:  Omer Celal Elcioglu; Abdullah Ozkok; Timur Selcuk Akpınar; Fatih Tufan; Murat Sezer; Sabahattin Umman; Sevgi Kalayoglu Besısık
Journal:  Int J Hematol       Date:  2012-07-06       Impact factor: 2.490

  2 in total

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