Literature DB >> 16785803

Thyroid cancer presenting as a PET incidentaloma in a patient with concomitant breast cancer metastases to the thyroid.

Rébecca Leboeuf1, François Bénard, Marie-France Langlois.   

Abstract

INTRODUCTION: Metastases to the thyroid gland are considered a rare cause of thyroid tumor. Furthermore, a relationship between breast and thyroid carcinoma has been previously proposed. CASE DESCRIPTION: We describe the case of a 59-year-old woman who presented with simultaneous papillary and breast carcinoma within the thyroid gland. F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) done for the evaluation of her metastatic breast cancer revealed a thyroid incidentaloma with a high metabolic rate (standardized uptake value [SUV] of 13). She underwent thyroidectomy and the pathology revealed papillary thyroid carcinoma corresponding to the lesion visualized on FDG PET. However, small metastatic implants of breast carcinoma were seen within the opposite thyroid lobe.
CONCLUSION: This is a rare description of a concomitant papillary thyroid carcinoma presenting as an FDG PET incidentaloma alongside breast cancer metastases to the thyroid gland. Thyroid and breast cancer sometimes occur in the same patient. However, no explanation has been found to link these 2 cancers. Although uncommon, FDG PET thyroid incidentalomas seem to harbor a higher rate of malignancy than incidentalomas found on conventional imaging. In the appropriate clinical setting, it is therefore suggested to investigate these lesions thoroughly.

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Year:  2006        PMID: 16785803     DOI: 10.1097/01.rlu.0000222677.50747.be

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


  4 in total

1.  Detection of Thyroid Metastasis of Renal Transitional Cell Carcinoma Using FDG PET/CT.

Authors:  Yong-Il Kim; Jong Jin Lee; Jin Ho Paik; Yu Kyeong Kim; Sang Eun Kim
Journal:  Nucl Med Mol Imaging       Date:  2011-03-22

2.  Metastasis to the thyroid gland from primary breast cancer presenting as diffuse goiter: A case report and review of literature.

Authors:  Wen Wen; Heng Jiang; Hsin-Yu Wen; Yu-Lan Peng
Journal:  World J Clin Cases       Date:  2022-01-21       Impact factor: 1.337

3.  Bilateral diffuse fluorodeoxyglucose uptake in thyroid gland diagnosed by fluorodeoxyglucose-positron emission tomography/computed tomography.

Authors:  Aung Zaw Win; Carina Mari Aparici
Journal:  World J Nucl Med       Date:  2014-05

Review 4.  Rare sites of breast cancer metastasis: a review.

Authors:  Rosa Di Micco; Letizia Santurro; Maria Luisa Gasparri; Veronica Zuber; Enrico Fiacco; Guglielmo Gazzetta; Chanel Elisha Smart; Alice Valentini; Oreste Davide Gentilini
Journal:  Transl Cancer Res       Date:  2019-10       Impact factor: 1.241

  4 in total

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