Literature DB >> 16785608

Adenine nucleotide pattern in rat pancreatic islets exposed to nutrient secretagogues.

Eda Agascioglu1, Marie-Hélène Giroix, Willy J Malaisse, Abdullah Sener.   

Abstract

The effects of D-glucose, D-mannose, D-galactose, Dglyceraldehyde, pyruvate, L-lactate, 2-ketoisocaproate, L-leucine, and/or L-glutamine on the ATP and ADP content of rat isolated pancreatic islets were reevaluated in order to compare changes evoked by these nutrient secretagogues in the islet ATP content and ATP/ADP ratio to their effects upon insulin release. Although being compatible with the fuel concept for nutrient-stimulated insulin secretion, the results of this study also argue against the monolithic view that the adenine nucleotide pattern in islet cells represents the sole coupling factor between metabolic and more distal events in the process of nutrient-stimulated insulin release.

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Year:  2006        PMID： 16785608     DOI： 10.1385/ENDO:29:2:325

Source DB:  PubMed          Journal:  Endocrine        ISSN： 1355-008X            Impact factor:   3.633


  26 in total

1.  The stimulus secretion coupling of glucose-induced insulin release.

Authors:  W J Malaisse; S Kawazu; A Herchuelz; J C Hutton; G Somers; G Devis; A Sener
Journal:  Arch Biochem Biophys       Date:  1979-04-15       Impact factor: 4.013

2.  The stimulus-secretion coupling of glucose-induced insulin release. XXII. Qualitative and quantitative aspects of glycolysis in isolated islets.

Authors:  W J Malaisse; A Sener; J Levy; A Herchuelz
Journal:  Acta Diabetol Lat       Date:  1976 Sep-Dec

3.  The stimulus-secretion coupling of amino acid-induced insulin release. Biosynthetic and secretory responses of rat pancreatic islet to L-leucine and L-glutamine.

Authors:  A Sener; G Somers; G Devis; W J Malaisse
Journal:  Diabetologia       Date:  1981-08       Impact factor: 10.122

4.  Similarities in the stimulus-secretion coupling mechanisms of glucose- and 2-keto acid-induced insulin release.

Authors:  J C Hutton; A Sener; A Herchuelz; I Atwater; S Kawazu; A C Boschero; G Somers; G Devis; W J Malaisse
Journal:  Endocrinology       Date:  1980-01       Impact factor: 4.736

5.  Interference of glycogenolysis with glycolysis in pancreatic islets from glucose-infused rats.

Authors:  W J Malaisse; C Maggetto; V Leclercq-Meyer; A Sener
Journal:  J Clin Invest       Date:  1993-02       Impact factor: 14.808

6.  The stimulus-secretion coupling of glucose-induced insulin release. Effect of exogenous pyruvate on islet function.

Authors:  A Sener; S Kawazu; J C Hutton; A C Boschero; G Devis; G Somers; A Herchuelz; W J Malaisse
Journal:  Biochem J       Date:  1978-10-15       Impact factor: 3.857

7.  The stimulus-secretion coupling of glucose-induced insulin release. XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets.

Authors:  W J Malaisse; A Sener; A R Carpinelli; K Anjaneyulu; P Lebrun; A Herchuelz; J Christophe
Journal:  Mol Cell Endocrinol       Date:  1980-11       Impact factor: 4.102

8.  The stimulus--secretion coupling 4-methyl-2-oxopentanoate-induced insulin release.

Authors:  J C Hutton; A Sener; W J Malaisse
Journal:  Biochem J       Date:  1979-11-15       Impact factor: 3.857

9.  Hexose metabolism in pancreatic islets. Galactose transport, phosphorylation and oxidation.

Authors:  M H Giroix; F Malaisse-Lagae; A Sener; W J Malaisse
Journal:  Mol Cell Biochem       Date:  1985-02       Impact factor: 3.396

10.  Regulation of 86Rb outflow from pancreatic islets: the dual effect of nutrient secretagogues.

Authors:  A R Carpinelli; W J Malaisse
Journal:  J Physiol       Date:  1981-06       Impact factor: 5.182
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  2 in total

1.  The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells.

Authors:  P Huypens; R Pillai; T Sheinin; S Schaefer; M Huang; M L Odegaard; S M Ronnebaum; S D Wettig; J W Joseph
Journal:  Diabetologia       Date:  2010-10-15       Impact factor: 10.122

2.  The role of α-ketoglutarate and the hypoxia sensing pathway in the regulation of pancreatic β-cell function.

Authors:  M Hoang; J W Joseph
Journal:  Islets       Date:  2020-09-02       Impact factor: 2.694
  2 in total

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