| Literature DB >> 16784975 |
Vítor Trovisco1, Paula Soares, Manuel Sobrinho-Simões.
Abstract
The very recent discovery of B-RAF point mutations as the most prevalent genetic alteration in papillary thyroid carcinoma has revolutionized the molecular knowledge of thyroid malignancies. In this review, we address the role played by such mutations in the etiopathogenesis, diagnosis, prognosis, and therapy selection of thyroid cancer, with an emphasis on papillary carcinoma.Entities:
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Year: 2006 PMID： 16784975 DOI： 10.1016/j.humpath.2006.03.013
Source DB: PubMed Journal: Hum Pathol ISSN： 0046-8177 Impact factor: 3.466