Literature DB >> 16784177

Prevalence of microalbuminuria and hypertension in South Asians and white Europeans with type 2 diabetes: a report from the United Kingdom Asian Diabetes Study (UKADS).

Anthony N Dixon1, Neil T Raymond, Shanaz Mughal, Asad Rahim, J Paul O'Hare, Sudhesh Kumar, Anthony H Barnett.   

Abstract

Microalbuminuria is more common in South Asian individuals compared to white Europeans. The aim of this study was to determine the relationship between blood pressure and microalbuminuria in a cohort of patients with type 2 diabetes in these two ethnic groups. These further data were analysed from 552 patients (311 South Asian patients and 241 white Europeans) who had microalbuminuria screening data collected. Prevalence of microalbuminuria was significantly higher in South Asian compared with white European patients (31% versus 20%, p=0.007). Among patients with normal, untreated blood pressure, the proportion who had microalbuminuria was three times higher among South Asian patients compared with the white European group (30.7% versus 10.1%, p=0.049, relative risk = 3.1 [1.0-9.5]). In addition, despite their higher cardiovascular risk, South Asian patients were less likely to be prescribed a statin or antihypertensive drug treatment. In conclusion, thresholds and targets for treatment of cardiovascular risk factors in South Asians may need to be lower than those for white Europeans, and targeted intervention will be required to achieve this.

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Year:  2006        PMID: 16784177     DOI: 10.3132/dvdr.2006.002

Source DB:  PubMed          Journal:  Diab Vasc Dis Res        ISSN: 1479-1641            Impact factor:   3.291


  8 in total

1.  Prevalence and correlates of diabetes in South asian indians in the United States: findings from the metabolic syndrome and atherosclerosis in South asians living in america study and the multi-ethnic study of atherosclerosis.

Authors:  A M Kanaya; C L Wassel; D Mathur; A Stewart; D Herrington; M J Budoff; V Ranpura; K Liu
Journal:  Metab Syndr Relat Disord       Date:  2010-04       Impact factor: 1.894

2.  Overview of the i-SEARCH Global Study : Cardiovascular Risk Factors and Microalbuminuria in Hypertensive Individuals.

Authors:  Michael Böhm; Martin Thoenes; Nicolas Danchin; Jan C Reil; Massimo Volpe
Journal:  High Blood Press Cardiovasc Prev       Date:  2013-01-22

Review 3.  Clinical correlates and pharmacological management of Asian patients with concomitant diabetes mellitus and heart failure.

Authors:  Yvonne May Fen Chia; Tiew-Hwa Katherine Teng; Chanchal Chandramouli; Jonathan Yap; Michael MacDonald; Carolyn S P Lam
Journal:  Heart Fail Rev       Date:  2018-05       Impact factor: 4.214

Review 4.  Diabetes and associated complications in the South Asian population.

Authors:  Arti Shah; Alka M Kanaya
Journal:  Curr Cardiol Rep       Date:  2014-05       Impact factor: 2.931

5.  Microcirculatory rarefaction in South Asians - a potential mechanism for increased cardiovascular risk and diabetes.

Authors:  Alun D Hughes; Raj Bathula; Chloe Park; Therese Tillin; Nicholas Wit; Simon McG Thom; Nish Chaturvedi
Journal:  PLoS One       Date:  2013-10-07       Impact factor: 3.240

6.  Outcomes of patients with COVID-19 on kidney replacement therapy: a comparison among modalities in England.

Authors:  Manuela Savino; Shalini Santhakumaran; Katharine M Evans; Retha Steenkamp; Fran Benoy-Deeney; James F Medcalf; Dorothea Nitsch
Journal:  Clin Kidney J       Date:  2021-09-04

7.  Protocol of an observational study to evaluate diabetic nephropathy through detection of microalbuminuria in Indian patients.

Authors:  Manisha Sahay; Sanjay Kalra; Vijay Vishwanathan; Abdul Hamid Zargar; Pradeep G Talwalkar; Subhash Kuamr Wangnoo; Debasish Maji; G Vijay Kumar; Ramesh Kumar Sharma; Deodatta Chafekar; Brij Mohan; Ganapathi Bantwal; Anil Bansali; Jasmeet Singh Sahni
Journal:  Indian J Endocrinol Metab       Date:  2013-05

8.  Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis.

Authors:  Manuela Savino; Anna Casula; Shalini Santhakumaran; David Pitcher; Esther Wong; Winnie Magadi; Katharine M Evans; Fran Benoy-Deeney; James Griffin; Lucy Plumb; Retha Steenkamp; Dorothea Nitsch; James Medcalf
Journal:  PLoS One       Date:  2020-10-23       Impact factor: 3.240

  8 in total

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