Literature DB >> 16782347

Synthesis of aromatic C-xylosides by position inversion of glucose.

Jesper Malmberg1, Katrin Mani, Elin Säwén, Anders Wirén, Ulf Ellervik.   

Abstract

Two formally C-xylosylated analogs to 2-naphthyl beta-D-xylopyranoside, which is known to initiate priming of glucosaminoglycan chains, were synthesized by a position inversion of glucose (i.e., position 1 becomes position 5). The D-C-xyloside showed priming, while the L-C-xyloside did not initiate priming.

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Year:  2006        PMID: 16782347     DOI: 10.1016/j.bmc.2006.05.068

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

1.  Investigating the elusive mechanism of glycosaminoglycan biosynthesis.

Authors:  Xylophone V Victor; Thao K N Nguyen; Manivannan Ethirajan; Vy M Tran; Khiem V Nguyen; Balagurunathan Kuberan
Journal:  J Biol Chem       Date:  2009-07-23       Impact factor: 5.157

2.  Synthesis of fluorophore-tagged xylosides that prime glycosaminoglycan chains.

Authors:  Vy M Tran; Balagurunathan Kuberan
Journal:  Bioconjug Chem       Date:  2014-02-05       Impact factor: 4.774

  2 in total

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