Literature DB >> 16781237

Door-to-drug and door-to-balloon times: where can we improve? Time to reperfusion therapy in patients with ST-segment elevation myocardial infarction (STEMI).

Elizabeth H Bradley1, Jeph Herrin, Yongfei Wang, Robert L McNamara, Martha J Radford, David J Magid, John G Canto, Martha Blaney, Harlan M Krumholz.   

Abstract

BACKGROUND: To better understand hospital performance in door-to-drug and door-to-balloon times for patients with STEMI, we examined hospital-level variation in key subintervals of door-to-drug time (door-to-electrocardiogram [ECG] and ECG-to-drug) and of door-to-balloon time (door-to-ECG, ECG-to-lab, lab-to-balloon). We sought to identify achievable subinterval times based on the experience of top performing hospitals.
METHODS: We conducted a cross-sectional analysis, using data from the National Registry of Myocardial Infarction, of admissions between January 1, 2001, and December 31, 2002 (20435 patients receiving fibrinolytic therapy in 693 hospitals, and 13387 patients receiving percutaneous coronary intervention in 340 hospitals). Using hierarchical regression modeling, we estimated hospital-level geometric means of each subinterval, adjusted for patient clinical characteristics. We ranked hospitals based on the proportion of patients treated within 30 minutes for door-to-drug time and 90 minutes for door-to-balloon times and compared adjusted subinterval times across these groups.
RESULTS: The higher performing hospitals (top 20%) in door-to-drug time and door-to-balloon times had significantly shorter times in nearly all subintervals compared with other hospitals, adjusted for patient clinical characteristics. Adjusted mean subinterval times in higher performing hospitals in door-to-drug time were 6.8 minutes (SD = 1.7) for door-to-ECG and 18.7 minutes (SD = 3.5) for ECG-to-drug. Adjusted mean subinterval times in higher performing hospitals in door-to-balloon time were 7.9 minutes (SD = 1.7) for door-to-ECG, 47.8 minutes (SD = 7.1) for ECG-to-lab, and 29.0 minutes (5.4) for lab-to-balloon, adjusted for patient clinical characteristics.
CONCLUSIONS: Substantial national attention is being directed at improving time to treatment of patients with STEMI. These data suggest achievable subinterval times for hospitals seeking to improve performance in this important quality indicator.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16781237     DOI: 10.1016/j.ahj.2005.07.015

Source DB:  PubMed          Journal:  Am Heart J        ISSN: 0002-8703            Impact factor:   4.749


  19 in total

Review 1.  Timely and optimal treatment of patients with STEMI.

Authors:  Jens F Lassen; Hans E Bøtker; Christian J Terkelsen
Journal:  Nat Rev Cardiol       Date:  2012-11-20       Impact factor: 32.419

Review 2.  Timely reperfusion for ST-segment elevation myocardial infarction: Effect of direct transfer to primary angioplasty on time delays and clinical outcomes.

Authors:  Rodrigo Estévez-Loureiro; Angela López-Sainz; Armando Pérez de Prado; Carlos Cuellas; Ramón Calviño Santos; Norberto Alonso-Orcajo; Jorge Salgado Fernández; Jose Manuel Vázquez-Rodríguez; Maria López-Benito; Felipe Fernández-Vázquez
Journal:  World J Cardiol       Date:  2014-06-26

3.  Improvements in door-to-balloon time in the United States, 2005 to 2010.

Authors:  Harlan M Krumholz; Jeph Herrin; Lauren E Miller; Elizabeth E Drye; Shari M Ling; Lein F Han; Michael T Rapp; Elizabeth H Bradley; Brahmajee K Nallamothu; Wato Nsa; Dale W Bratzler; Jeptha P Curtis
Journal:  Circulation       Date:  2011-08-22       Impact factor: 29.690

4.  Hospital readmissions reduction program.

Authors:  Colleen K McIlvennan; Zubin J Eapen; Larry A Allen
Journal:  Circulation       Date:  2015-05-19       Impact factor: 29.690

5.  Door-to-balloon: where do we lose time? Single centre experience in India.

Authors:  Suma M Victor; Anand Gnanaraj; Vijayakumar S; Sushanth Pattabiram; Ajit S Mullasari
Journal:  Indian Heart J       Date:  2012-09-12

6.  Emergency Department Activation of Interventional Cardiology to Reduce Door-to-Balloon Time.

Authors:  Simon A Mahler; Hoi Y Chan; Donna L Carden; Christopher Wolcott; Steven A Conrad
Journal:  West J Emerg Med       Date:  2010-09

7.  Use of the prehospital ECG improves door-to-balloon times in ST segment elevation myocardial infarction irrespective of time of day or day of week.

Authors:  Bosede A Afolabi; Gian M Novaro; Sergio L Pinski; Kenneth R Fromkin; Howard S Bush
Journal:  Emerg Med J       Date:  2007-08       Impact factor: 2.740

8.  Patterns of change in nesiritide use in patients with heart failure: how hospitals react to new information.

Authors:  Chohreh Partovian; Shu-Xia Li; Xiao Xu; Haiqun Lin; Kelly M Strait; John Hwa; Harlan M Krumholz
Journal:  JACC Heart Fail       Date:  2013-08-05       Impact factor: 12.035

9.  Factors associated with presenting >12 hours after symptom onset of acute myocardial infarction among Veteran men.

Authors:  Kelly McDermott; Charles Maynard; Ranak Trivedi; Elliott Lowy; Stephan Fihn
Journal:  BMC Cardiovasc Disord       Date:  2012-09-28       Impact factor: 2.298

10.  Factors Influencing Time-Dependent Quality Indicators for Patients With Suspected Acute Coronary Syndrome.

Authors:  Daniel J France; Scott Levin; Ru Ding; Robin Hemphill; Jin Han; Stephan Russ; Dominik Aronsky; Matt Weinger
Journal:  J Patient Saf       Date:  2020-03       Impact factor: 2.243

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.