Literature DB >> 167798

Cyclic AMP in skin: effects of acute ischaemia.

K Yoshikawa, K Adachi, K M Halprin, V Levine.   

Abstract

The cyclic adenosine 3',5'-monophosphate (cyclic AMP) content of pig skin was measured several seconds to minutes after removal of the skin from the body. It increased very rapidly, reached a maximum by 2 min after removal (4 times higher than the initial level), then decreased very slowly. Propranolol injected into the animal before or added after the removal of the skin did not suppress this phenomenon. The practical significance of this finding (increase of cyclic AMP level in skin after ischaemia) is obvious-in order to measure cyclic AMP level in vivo, the sample must be frozen immediately to avoid an 'artificial' increase in cyclic AMP.

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Year:  1975        PMID： 167798     DOI： 10.1111/j.1365-2133.1975.tb03073.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN： 0007-0963            Impact factor:   9.302


  8 in total

1.  Glucocorticoid-induced alteration of beta-adrenergic adenylate cyclase response of epidermis.

Authors:  A Ohkawara; H Iizuka
Journal:  Arch Dermatol Res       Date:  1985       Impact factor: 3.017

2.  A dose-response study of adrenaline combined with lignocaine 2%: effect on acute postoperative pain after oral soft tissue surgery.

Authors:  L Jorkjend; L A Skoglund
Journal:  Br J Clin Pharmacol       Date:  2001-04       Impact factor: 4.335

3.  Immunohistochemical localization of cyclic nucleotides in guinea pig lip.

Authors:  Y Miyachi; S Imamura; C Tanaka; T Kuno; N Yoshida
Journal:  Arch Dermatol Res       Date:  1980       Impact factor: 3.017

4.  Cyclosporin A induced augmentation of the beta-adrenergic adenylate cyclase response of pig epidermis.

Authors:  N Kato; K M Halprin; J R Taylor; A Ohkawara
Journal:  Arch Dermatol Res       Date:  1988       Impact factor: 3.017

5.  Effect of in vitro cultivation and Mycoplasma pneumoniae infection on intracellular cyclic AMP levels in hamster tracheal organ cultures.

Authors:  B K Wolffing; M G Gabridge
Journal:  In Vitro       Date:  1979-04

6.  Modulation of pig epidermal adenylate-cyclase responses by protein-synthesis inhibitors: its relation to glucocorticoid and colchicine effects.

Authors:  H Iizuka; K Kishiyama; N Ohkuma; A Ohkawara
Journal:  Arch Dermatol Res       Date:  1985       Impact factor: 3.017

7.  Cyclic AMP accumulation in the beta adrenergic mechanism of eccrine sweat secretion.

Authors:  K Sato; F Sato
Journal:  Pflugers Arch       Date:  1981-04       Impact factor: 3.657

8.  Dimethyl sulfoxide-induced augmentation of adenosine-adenylate cyclase response of pig skin epidermis.

Authors:  M Watanabe; H Iizuka
Journal:  Arch Dermatol Res       Date:  1986       Impact factor: 3.017
  8 in total

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