| Literature DB >> 16779299 |
Tien-Hsiung Ku1, Fang Rong Hsu.
Abstract
Among 75218 splicing sites, 137 colon cancer specific alternative splicing isoforms were found by mining EST database. Alternative splicing database were first constructed by aligning EST to genomic sequence. Numbers of ESTs from normal or cancer colon tissue supporting splicing isoform at each splicing site were then queried and analyzed with Fisher exact test. There were 53 3' splicing, 42 5' splicing, 40 exon skipping and 2 mutual exclusive cancer specific splicing isoforms.Entities:
Mesh：
Year: 2005 PMID： 16779299 PMCID： PMC1560692
Source DB: PubMed Journal: AMIA Annu Symp Proc ISSN： 1559-4076