Literature DB >> 16778813

A new wrinkle on topical vitamin E and photo-inflammation: Mechanistic studies of a hydrophilic gamma-tocopherol derivative compared with alpha-tocopherol.

Raymond L Konger1.   

Abstract

The antioxidant function of vitamin E is thought to mediate its photo-protective effects. Cyclooxygenase-2 (COX-2) is an important mediator of early photo-inflammation. Thus, the ability of gamma-tocopherol to inhibit COX-2 activity independently of its antioxidant function raises important questions regarding potential roles that this form of vitamin E plays in photo-protection and skin cancer chemoprevention.

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Year:  2006        PMID： 16778813     DOI： 10.1038/sj.jid.5700308

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  4 in total

Review 1.  Isoforms of vitamin E differentially regulate inflammation.

Authors:  Joan M Cook-Mills; Christine A McCary
Journal:  Endocr Metab Immune Disord Drug Targets       Date:  2010-12       Impact factor: 2.895

Review 2.  Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants.

Authors:  Joan M Cook-Mills; Michelle E Marchese; Hiam Abdala-Valencia
Journal:  Antioxid Redox Signal       Date:  2011-05-11       Impact factor: 8.401

3.  Addressing Free Radical Oxidation in Acne Vulgaris.

Authors:  Otto H Mills; Maressa C Criscito; Todd E Schlesinger; Robert Verdicchio; Ernest Szoke
Journal:  J Clin Aesthet Dermatol       Date:  2016-01

4.  Isoforms of vitamin E have opposing immunoregulatory functions during inflammation by regulating leukocyte recruitment.

Authors:  Sergejs Berdnikovs; Hiam Abdala-Valencia; Christine McCary; Michelle Somand; Rokeisha Cole; Alex Garcia; Paul Bryce; Joan M Cook-Mills
Journal:  J Immunol       Date:  2009-04-01       Impact factor: 5.422
  4 in total

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