Literature DB >> 16778594

Knowledge and attitudes concerning medical genetics amongst physicians and medical students in Cameroon (sub-Saharan Africa).

Ambroise Wonkam1, Alfred K Njamnshi, Fru F Angwafo.   

Abstract

PURPOSE: Little is known about physician's knowledge of, and attitudes toward genetics in sub-Saharan Africa.
METHODS: Survey of 101 pre-clinical, 95 clinical medical students, and 110 physicians, in Cameroon.
RESULTS: The awareness of DNA diagnosis was poor: 0, 2.2, and 1.2%, respectively, for sickle cell anemia. The majority of the respondents considered genetic counseling as indispensable (97.6, 98.9 and 100%); and prenatal diagnosis as acceptable. The acceptance of medical abortion increased with the level of medical education (62.6, 74.7 and 90.7%). Sickle cell anemia was considered as a "serious disease" by a greater majority of respondents than Down syndrome (P < 0.001). But, in all three groups, the acceptance of termination of affected pregnancy "if the respondent's own child was affected" was lower for sickle cell anemia than Down syndrome (22.4 versus 40.2%, 10.8 versus 29.3% and 36.1 versus 70.4%).
CONCLUSIONS: The data suggest a poor knowledge of genetic tests among medical students and physicians. This cohort appears to accept the principles of medical genetics. Our data emphasized a need to introduce genetics and to develop research on its ethical and social implications in Cameroon.

Entities:  

Mesh:

Year:  2006        PMID: 16778594     DOI: 10.1097/01.gim.0000223542.97262.21

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  26 in total

1.  Acceptability of prenatal diagnosis by a sample of parents of sickle cell anemia patients in Cameroon (sub-Saharan Africa).

Authors:  Ambroise Wonkam; Alfred K Njamnshi; Dora Mbanya; Jeanne Ngogang; Caryl Zameyo; Fru F Angwafo
Journal:  J Genet Couns       Date:  2011-05-21       Impact factor: 2.537

2.  A call for policy action in sub-Saharan Africa to rethink diagnostics for pregnancy affected by sickle cell disease: differential views of medical doctors, parents and adult patients predict value conflicts in Cameroon.

Authors:  Ambroise Wonkam; Samia Hurst
Journal:  OMICS       Date:  2014-04-22

3.  Hospital nursing leadership-led interventions increased genomic awareness and educational intent in Magnet settings.

Authors:  Kathleen A Calzone; Jean Jenkins; Stacey Culp; Laurie Badzek
Journal:  Nurs Outlook       Date:  2017-11-13       Impact factor: 3.250

4.  Developing clinical cancer genetics services in resource-limited countries: the case of retinoblastoma in Kenya.

Authors:  Li Qun He; Lucy Njambi; Joseph M Nyamori; Emmanuel M Nyenze; Kahaki Kimani; Ibrahim Matende; Hilary Rono; Victor Njom; James Bett; Mukiri Mukuria; Muchai Gachago; Helen Roberts; Helen Dimaras
Journal:  Public Health Genomics       Date:  2014-07-19       Impact factor: 2.000

5.  Ethical, social, and cultural issues related to clinical genetic testing and counseling in low- and middle-income countries: a systematic review.

Authors:  Adrina Zhong; Benedict Darren; Bethina Loiseau; Li Qun Betty He; Trillium Chang; Jessica Hill; Helen Dimaras
Journal:  Genet Med       Date:  2018-08-03       Impact factor: 8.822

6.  Perspectives in Genetics and Sickle Cell Disease Prevention in Africa: Beyond the Preliminary Data from Cameroon.

Authors:  Ambroise Wonkam; Valentina Josiane Ngo Bitoungui; Jeanne Ngogang
Journal:  Public Health Genomics       Date:  2015-06-04       Impact factor: 2.132

7.  Genomics governance: advancing justice, fairness and equity through the lens of the African communitarian ethic of Ubuntu.

Authors:  Nchangwi Syntia Munung; Jantina de Vries; Bridget Pratt
Journal:  Med Health Care Philos       Date:  2021-04-02

Review 8.  Community engagement strategies for genomic studies in Africa: a review of the literature.

Authors:  Paulina Tindana; Jantina de Vries; Megan Campbell; Katherine Littler; Janet Seeley; Patricia Marshall; Jennifer Troyer; Morisola Ogundipe; Vincent Pius Alibu; Aminu Yakubu; Michael Parker
Journal:  BMC Med Ethics       Date:  2015-04-12       Impact factor: 2.652

9.  Success stories in genomic medicine from resource-limited countries.

Authors:  Konstantinos Mitropoulos; Hayat Al Jaibeji; Diego A Forero; Paul Laissue; Ambroise Wonkam; Catalina Lopez-Correa; Zahurin Mohamed; Wasun Chantratita; Ming Ta Michael Lee; Adrian Llerena; Angela Brand; Bassam R Ali; George P Patrinos
Journal:  Hum Genomics       Date:  2015-06-18       Impact factor: 4.639

10.  The impact of needs-based education on the change of knowledge and attitudes towards medical genetics in medical students.

Authors:  Paola Čargonja; Martina Mavrinac; Saša Ostojić; Nina Pereza
Journal:  Eur J Hum Genet       Date:  2021-01-04       Impact factor: 5.351

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