Variability of exposure and estimation of cumulative exposure in a manually operated coal mine.

This study aims at estimating variability in exposure to respirable dust and assessing whether the a priori grouping by job team is appropriate for an exposure-response study on respiratory effects among workers in a manually operated coal mine in Tanzania. Furthermore, estimated exposure levels were used to calculate cumulative exposure. Full-shift personal respirable dust samples (n = 204) were collected from 141 randomly chosen workers at underground and surface work sites. The geometric mean exposure for respirable dust varied from 0.07 mg m(-3) for office workers to 1.96 mg m(-3) for the development team. The analogous range of respirable quartz exposure was 0.006-0.073 mg m(-3). Variance components were estimated using random effect models. For most job teams the within-worker variance component was considerably higher than the between-worker variance component. For respirable dust the estimated attenuation of the linear exposure-response relationship was low (5.9%) when grouping by job team. Grouping by job team was considered appropriate for studying the association between current dust exposure and respiratory effects. Based on the estimated worker-specific mean exposure in the job teams, the arithmetic mean cumulative exposure for the 299 workers who participated in the epidemiological part of the study was 38.1 mg* yr m(-3) for respirable dust and 2.0 mg* yr m(-3) for quartz.