| Literature DB >> 16777595 |
Ivone Bruno1, Miles F Wilkinson.
Abstract
P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.Mesh：
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Year: 2006 PMID： 16777595 DOI： 10.1016/j.cell.2006.06.003
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582