Literature DB >> 16777240

Staging and surgical approaches in large juvenile angiofibroma--study of 95 cases.

Isha Tyagi1, Rajan Syal, Amit Goyal.   

Abstract

INTRODUCTION: Surgery has been the treatment of choice for juvenile nasopharyngeal angiofibroma (JNA) and selection of proper surgical approach depends primarily upon the extensions of the tumor. Minimal external deformity/surgical scar without affecting growth pattern of facial skeleton of patient along with extensions of JNA were the basis of selecting surgical approach in present study.
MATERIAL AND METHODS: The medical records of 95 patients with histologically proven large JNA who underwent treatment in our institution between 1992 and 2002 were reviewed retrospectively. Inclusion criterion-Stage II, III, IV JNA, minimum available follow up of 2 years. Exclusion criterion-Stage I JNA, follow up of less than 2 years. Lazy S incision was used and combined transmaxillary and transpalatal removal of angiofibroma was done in most of the cases.
RESULTS: Complete removal of JNA was achieved in 78 (82%) cases in single surgery. Residual tumor was found in 17 (18%) cases.
CONCLUSIONS: Infratemporal, pterygopalatine, orbital and intracranial extensions of JNA (Stage IIIa and IIIb) can be removed by combined transpalatal and transmaxillary approach by Lazy S incision without producing any facial asymmetry or cosmetic defect. Conservative lateral infratemporal approach (type D1 approach) is required in very large lateral extensions or where JNA is extending intracranially through foramen ovale. Staged fronto-temporal craniotomy should be done in Stage IVa tumors (large intracranial extensions). In Stage IVb tumors (invading cavernous sinus), usually residual tumor remains which should be followed subsequently.

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Year:  2006        PMID: 16777240     DOI: 10.1016/j.ijporl.2006.05.004

Source DB:  PubMed          Journal:  Int J Pediatr Otorhinolaryngol        ISSN: 0165-5876            Impact factor:   1.675


  7 in total

1.  Progressive epistaxis in two young males: Classic presentations of juvenile nasopharyngeal angiofibroma in unusual locations.

Authors:  Christopher Harker Hunt; Jonathan M Morris; Peter U Lee; Harry Cloft
Journal:  Neuroradiology       Date:  2010-02-02       Impact factor: 2.804

2.  Clinical Characteristics of Recurrent Juvenile Nasopharyngeal Angiofibroma (JNA) After Radiation Therapy.

Authors:  Ozan Gökdoğan; Beyhan Demirhan; Ahmet Koybasioglu; Fikret İleri
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2015-05-29

3.  Juvenile nasopharyngeal angiofibroma: current treatment modalities and future considerations.

Authors:  John M Hodges; A S McDevitt; A I El-Sayed Ali; M E Sebelik
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2010-10-12

4.  Management and Outcome in Patients with Advanced Juvenile Nasopharyngeal Angiofibroma.

Authors:  Vedantam Rupa; Sunithi Elizabeth Mani; Selvamani Backianathan; Vedantam Rajshekhar
Journal:  J Neurol Surg B Skull Base       Date:  2017-11-27

5.  Long-term treatment outcomes of juvenile nasopharyngeal angiofibroma treated with radiotherapy.

Authors:  S Mallick; R Benson; S Bhasker; B K Mohanti
Journal:  Acta Otorhinolaryngol Ital       Date:  2015-04       Impact factor: 2.124

6.  Angiofibroma Localized in the Sphenoid Sinus.

Authors:  Alper Yenigun; Fadlullah Aksoy; Omer Vural; Orhan Ozturan
Journal:  Case Rep Otolaryngol       Date:  2017-11-22

7.  Two types of lateral extension in juvenile nasopharyngeal angiofibroma: diagnostic and therapeutic management.

Authors:  Anna Szymańska; Marcin Szymański; Elżbieta Czekajska-Chehab; Małgorzata Szczerbo-Trojanowska
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-03-06       Impact factor: 2.503

  7 in total

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