Literature DB >> 1677609

Dynamic changes in extracellular fluid ascorbic acid monitored by in vivo electrochemistry.

B Ghasemzadeh1, J Cammack, R N Adams, B Ghasemzedah.   

Abstract

Voltammetric carbon fiber electrodes and a measuring protocol were designed to monitor extracellular changes in rat brain ascorbic acid (AA). Very fast variations of AA (less than 60 s in duration) as well as much slower changes can be followed. Basal and stimulated levels of AA, determined with the enzyme ascorbate oxidase (AAO), confirm the detection is selective for AA. Microinjections of glutamate (Glu) into various brain regions gave rise to rapid electrochemical signals ascribed to the efflux of AA into the extracellular fluid.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1677609

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  14 in total

1.  A comparative study between a brain Na+,K(+)-ATPase inhibitor (endobain E) and ascorbic acid.

Authors:  G Rodríguez de Lores Arnaiz; T Herbin; C Peña
Journal:  Neurochem Res       Date:  2003-06       Impact factor: 3.996

2.  Ascorbate transport and recycling by SH-SY5Y neuroblastoma cells: response to glutamate toxicity.

Authors:  James M May; Liying Li; Kendra Hayslett; Zhi-chao Qu
Journal:  Neurochem Res       Date:  2006-06-22       Impact factor: 3.996

3.  Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington's disease: interactions between neurons and astrocytes.

Authors:  Ana María Estrada-Sánchez; George V Rebec
Journal:  Basal Ganglia       Date:  2012-07-01

4.  Electroenzymatic glutamate sensing at near the theoretical performance limit.

Authors:  I-Wen Huang; Mackenzie Clay; Siqi Wang; Yuwan Guo; Jingjing Nie; Harold G Monbouquette
Journal:  Analyst       Date:  2020-01-30       Impact factor: 4.616

5.  Corticostriatal dysfunction underlies diminished striatal ascorbate release in the R6/2 mouse model of Huntington's disease.

Authors:  Jenelle L Dorner; Benjamin R Miller; Emma L Klein; Alexander Murphy-Nakhnikian; Rachel L Andrews; Scott J Barton; George V Rebec
Journal:  Brain Res       Date:  2009-07-16       Impact factor: 3.252

6.  Behavioral activation in rats requires endogenous ascorbate release in striatum.

Authors:  G V Rebec; Z Wang
Journal:  J Neurosci       Date:  2001-01-15       Impact factor: 6.167

7.  Electrochemical monitoring of brain ascorbic acid changes associated with hypoxia, spreading depression, and seizure activity.

Authors:  J Cammack; B Ghasemzadeh; R N Adams
Journal:  Neurochem Res       Date:  1992-01       Impact factor: 3.996

8.  Ascorbic acid participates in a general mechanism for concerted glucose transport inhibition and lactate transport stimulation.

Authors:  Maite A Castro; Constanza Angulo; Sebastián Brauchi; Francisco Nualart; Ilona I Concha
Journal:  Pflugers Arch       Date:  2008-05-28       Impact factor: 3.657

9.  Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington's disease.

Authors:  Benjamin R Miller; Jenelle L Dorner; Kendra D Bunner; Thomas W Gaither; Emma L Klein; Scott J Barton; George V Rebec
Journal:  J Neurochem       Date:  2012-03-28       Impact factor: 5.372

10.  Dysregulation of corticostriatal ascorbate release and glutamate uptake in transgenic models of Huntington's disease.

Authors:  George V Rebec
Journal:  Antioxid Redox Signal       Date:  2013-06-19       Impact factor: 8.401
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.