BACKGROUND: Lipoblastoma and lipoblastomatosis are uncommon benign mesenchymal lesions that predominantly occur in infancy and early childhood. OBJECTIVE: To evaluate the imaging and histological features of lipoblastoma and lipoblastomatosis. MATERIALS AND METHODS: Retrospective review of the radiological and pathological findings in children with lipoblastoma and lipoblastomatosis treated at a single centre between 1997 and 2004. RESULTS: Eight children (median age 18 months) had undergone imaging and surgery at our institution. An infiltrative growth pattern was identified at imaging in two children with lipoblastomatosis, and a well-defined mass in six children with lipoblastoma. In all patients, imaging showed a lesion composed mostly, but not entirely, of fat. There were no recurrences at follow-up of between 1 and 91 months. CONCLUSION: In infancy and early childhood, the identification of a tumour composed mostly of fat should suggest the diagnosis of lipoblastoma or lipoblastomatosis.
BACKGROUND:Lipoblastoma and lipoblastomatosis are uncommon benign mesenchymal lesions that predominantly occur in infancy and early childhood. OBJECTIVE: To evaluate the imaging and histological features of lipoblastoma and lipoblastomatosis. MATERIALS AND METHODS: Retrospective review of the radiological and pathological findings in children with lipoblastoma and lipoblastomatosis treated at a single centre between 1997 and 2004. RESULTS: Eight children (median age 18 months) had undergone imaging and surgery at our institution. An infiltrative growth pattern was identified at imaging in two children with lipoblastomatosis, and a well-defined mass in six children with lipoblastoma. In all patients, imaging showed a lesion composed mostly, but not entirely, of fat. There were no recurrences at follow-up of between 1 and 91 months. CONCLUSION: In infancy and early childhood, the identification of a tumour composed mostly of fat should suggest the diagnosis of lipoblastoma or lipoblastomatosis.
Authors: Y Posey; E Valdivia; D L Persons; S Ally; D L Smith; C G Pantazis; S D Smith Journal: J Pediatr Hematol Oncol Date: 1998 Nov-Dec Impact factor: 1.289
Authors: Dyda Dao; Anna J Najor; Philip Y Sun; Forough Farrokhyar; Christopher R Moir; Michael B Ishitani Journal: Pediatr Surg Int Date: 2020-01-14 Impact factor: 1.827