Literature DB >> 16774545

Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele.

L J Kennedy1, S Quarmby, G M Happ, A Barnes, I K Ramsey, R M Dixon, B Catchpole, C Rusbridge, P A Graham, N S Hillbertz, C Roethel, W J Dodds, N G Carmichael, W E R Ollier.   

Abstract

Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.

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Year:  2006        PMID: 16774545     DOI: 10.1111/j.1399-0039.2006.00614.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN: 0001-2815


  17 in total

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Journal:  Immunogenetics       Date:  2011-10-26       Impact factor: 2.846

2.  Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs.

Authors:  Steven G Friedenberg; Greg Buhrman; Lhoucine Chdid; Natasha J Olby; Thierry Olivry; Julien Guillaumin; Theresa O'Toole; Robert Goggs; Lorna J Kennedy; Robert B Rose; Kathryn M Meurs
Journal:  Immunogenetics       Date:  2015-12-28       Impact factor: 2.846

3.  From caveman companion to medical innovator: genomic insights into the origin and evolution of domestic dogs.

Authors:  Heidi G Parker; Samuel F Gilbert
Journal:  Adv Genomics Genet       Date:  2015-06-12

4.  Expanded dog leukocyte antigen (DLA) single nucleotide polymorphism (SNP) genotyping reveals spurious class II associations.

Authors:  N Safra; N C Pedersen; Z Wolf; E G Johnson; H W Liu; A M Hughes; A Young; D L Bannasch
Journal:  Vet J       Date:  2011-07-07       Impact factor: 2.688

5.  Allelic combinations of promoter and exon 2 in DQB1 in dogs and wolves.

Authors:  Karin T Berggren; Jennifer M Seddon
Journal:  J Mol Evol       Date:  2008-06-27       Impact factor: 2.395

6.  Allelic diversity at the DLA-88 locus in Golden Retriever and Boxer breeds is limited.

Authors:  P Ross; A S Buntzman; B G Vincent; E N Grover; G S Gojanovich; E J Collins; J A Frelinger; P R Hess
Journal:  Tissue Antigens       Date:  2012-05-10

7.  DLA class II alleles are associated with risk for canine symmetrical lupoid onychodystrophy [corrected](SLO).

Authors:  Maria Wilbe; Martine Lund Ziener; Anita Aronsson; Charlotte Harlos; Katarina Sundberg; Elin Norberg; Lisa Andersson; Kerstin Lindblad-Toh; Ake Hedhammar; Göran Andersson; Frode Lingaas
Journal:  PLoS One       Date:  2010-08-23       Impact factor: 3.240

8.  Association of an MHC class II haplotype with increased risk of polymyositis in Hungarian Vizsla dogs.

Authors:  Jonathan Massey; Simon Rothwell; Clare Rusbridge; Anna Tauro; Diane Addicott; Hector Chinoy; Robert G Cooper; William E R Ollier; Lorna J Kennedy
Journal:  PLoS One       Date:  2013-02-14       Impact factor: 3.240

9.  A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12.

Authors:  Matteo Bianchi; Stina Dahlgren; Jonathan Massey; Elisabeth Dietschi; Marcin Kierczak; Martine Lund-Ziener; Katarina Sundberg; Stein Istre Thoresen; Olle Kämpe; Göran Andersson; William E R Ollier; Åke Hedhammar; Tosso Leeb; Kerstin Lindblad-Toh; Lorna J Kennedy; Frode Lingaas; Gerli Rosengren Pielberg
Journal:  PLoS One       Date:  2015-08-11       Impact factor: 3.240

10.  Genetics and epidemiology of hypothyroidism and symmetrical onychomadesis in the Gordon setter and the English setter.

Authors:  Martine Lund Ziener; Stina Dahlgren; Stein Istre Thoresen; Frode Lingaas
Journal:  Canine Genet Epidemiol       Date:  2015-08-21
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