OBJECTIVES: In the global effort to eliminate lymphatic filariasis, mass drug administrations (MDAs) are organised annually. The success of this strategy depends on achieving high levels of drug coverage, which reduce the number of persons with circulating microfilariae and consequently transmission. Persons who consistently fail to participate in MDAs represent a potential threat to the goal of filariasis elimination. We wanted to know the drug coverage, the proportion of persons who were systematically non-compliant and factors associated with this behaviour. METHODS: We conducted three surveys following the third annual MDA of a filariasis elimination program in Leogane, Haiti: (1) a total population survey to determine coverage; (2) an adult survey to determine non-compliance and associated factors and (3) an urban survey to make a rural-urban comparison. RESULTS: During the third MDA, the overall surveyed coverage was 78.5% [95% confidence interval (CI) 74.4-82.6] A survey among adult population showed coverage estimates for persons >14 years old of 59.4% (95% CI 52.0-66.7), 61.0% (95% CI 55.0-67.4) and 67.3% (95% CI 60.5-74.0), for the first, second and third MDA respectively. The coverage in rural areas (78.3%) was significantly higher than in urban areas (68.3%, P < 0.05). Of the population > 14 years of age, 18% never took the drugs during any of three MDAs. These persons did not differ significantly from MDA participants by age, gender or other characteristics that we assessed. CONCLUSION: More research is needed to identify characteristics of systematically non-compliant persons in order to refine health education messages and improve distribution strategies to increase drug coverage.
OBJECTIVES: In the global effort to eliminate lymphatic filariasis, mass drug administrations (MDAs) are organised annually. The success of this strategy depends on achieving high levels of drug coverage, which reduce the number of persons with circulating microfilariae and consequently transmission. Persons who consistently fail to participate in MDAs represent a potential threat to the goal of filariasis elimination. We wanted to know the drug coverage, the proportion of persons who were systematically non-compliant and factors associated with this behaviour. METHODS: We conducted three surveys following the third annual MDA of a filariasis elimination program in Leogane, Haiti: (1) a total population survey to determine coverage; (2) an adult survey to determine non-compliance and associated factors and (3) an urban survey to make a rural-urban comparison. RESULTS: During the third MDA, the overall surveyed coverage was 78.5% [95% confidence interval (CI) 74.4-82.6] A survey among adult population showed coverage estimates for persons >14 years old of 59.4% (95% CI 52.0-66.7), 61.0% (95% CI 55.0-67.4) and 67.3% (95% CI 60.5-74.0), for the first, second and third MDA respectively. The coverage in rural areas (78.3%) was significantly higher than in urban areas (68.3%, P < 0.05). Of the population > 14 years of age, 18% never took the drugs during any of three MDAs. These persons did not differ significantly from MDA participants by age, gender or other characteristics that we assessed. CONCLUSION: More research is needed to identify characteristics of systematically non-compliant persons in order to refine health education messages and improve distribution strategies to increase drug coverage.
Authors: Brittany A Eddy; Anna J Blackstock; John M Williamson; David G Addiss; Thomas G Streit; Valery M Beau de Rochars; Leanne M Fox Journal: Am J Trop Med Hyg Date: 2013-11-11 Impact factor: 2.345
Authors: Alexis Boyd; Kimberly Y Won; Shannon K McClintock; Catherine V Donovan; Sandra J Laney; Steven A Williams; Nils Pilotte; Thomas G Streit; Madsen V E Beau de Rochars; Patrick J Lammie Journal: PLoS Negl Trop Dis Date: 2010-03-23
Authors: Maged El-Setouhy; Khaled M Abd Elaziz; Hanan Helmy; Hoda A Farid; Hussein A Kamal; Reda M R Ramzy; William D Shannon; Gary J Weil Journal: Am J Trop Med Hyg Date: 2007-12 Impact factor: 2.345
Authors: Dominique Kyelem; Gautam Biswas; Moses J Bockarie; Mark H Bradley; Maged El-Setouhy; Peter U Fischer; Ralph H Henderson; James W Kazura; Patrick J Lammie; Sammy M Njenga; Eric A Ottesen; Kapa D Ramaiah; Frank O Richards; Gary J Weil; Steven A Williams Journal: Am J Trop Med Hyg Date: 2008-10 Impact factor: 2.345
Authors: Khaled M Abd Elaziz; Maged El-Setouhy; Mark H Bradley; Reda M R Ramzy; Gary J Weil Journal: Am J Trop Med Hyg Date: 2013-06-10 Impact factor: 2.345
Authors: Caroline A Grady; Madsen Beau de Rochars; Abdel N Direny; Jean Nicolas Orelus; Joyanna Wendt; Jeanne Radday; Els Mathieu; Jacquelin M Roberts; Thomas G Streit; David G Addiss; Patrick J Lammie Journal: Emerg Infect Dis Date: 2007-04 Impact factor: 6.883
Authors: Naomi Drexler; Charles H Washington; Maribeth Lovegrove; Caroline Grady; Marie Denise Milord; Thomas Streit; Patrick Lammie Journal: PLoS Negl Trop Dis Date: 2012-10-11