Literature DB >> 16770533

Molecular mechanisms of metastasis.

Dave S B Hoon1, Minoru Kitago, Joseph Kim, Takuji Mori, Adriano Piris, Katherine Szyfelbein, Martin C Mihm, S David Nathanson, Timothy P Padera, Ann F Chambers, Sharon A Vantyghem, Ian C MacDonald, Steven C Shivers, Marwan Alsarraj, Douglas S Reintgen, Bernward Passlick, Wulf Sienel, Klaus Pantel.   

Abstract

A major topic covered at the First International Symposium on Cancer Metastasis and the Lymphovascular System was the molecular mechanisms of metastasis. This has become of major interest in recent years as we have discovered new metastasis-related genes and gained understanding of the molecular events of lymphatic metastasis. The symposium covered new aspects and important questions related to the events of metastasis in both humans and animals. The basic and clinical related research covered in this topic represented many disciplines. The presentations showed novel findings and at the same time, raised many new unanswered questions, indicating the limited knowledge we still have regarding the molecular events of metastasis. The hope is that further unraveling of the direct and indirect molecular events of lymphatic metastasis will lead to new approaches in developing effective therapeutics.

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Year:  2006        PMID: 16770533     DOI: 10.1007/s10555-006-8500-x

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN: 0167-7659            Impact factor:   9.264


  22 in total

1.  Metastasis in an orthotopic murine model of melanoma is independent of RAS/RAF mutation.

Authors:  Gabriela I Rozenberg; Kimberly B Monahan; Chad Torrice; James E Bear; Norman E Sharpless
Journal:  Melanoma Res       Date:  2010-10       Impact factor: 3.599

2.  VEGF-C/Flt-4 axis in tumor cells contributes to the progression of oral squamous cell carcinoma via upregulating VEGF-C itself and contactin-1 in an autocrine manner.

Authors:  Seiji Shigetomi; Yorihisa Imanishi; Katsushi Shibata; Nobuya Sakai; Koji Sakamoto; Ryoichi Fujii; Noboru Habu; Kuninori Otsuka; Yoichiro Sato; Yoshihiro Watanabe; Masayuki Shimoda; Kaori Kameyama; Hiroyuki Ozawa; Toshiki Tomita; Kaoru Ogawa
Journal:  Am J Cancer Res       Date:  2018-10-01       Impact factor: 6.166

3.  In vitro invasive pattern of hepatocellular carcinoma cell line HCCLM9 based on three-dimensional cell culture and quantum dots molecular imaging.

Authors:  Min Fang; Chun-Wei Peng; Shao-Ping Liu; Jing-Ping Yuan; Yan Li
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2013-08-01

Review 4.  Progression of cutaneous melanoma: implications for treatment.

Authors:  Stanley P L Leong; Martin C Mihm; George F Murphy; Dave S B Hoon; Mohammed Kashani-Sabet; Sanjiv S Agarwala; Jonathan S Zager; Axel Hauschild; Vernon K Sondak; Valerie Guild; John M Kirkwood
Journal:  Clin Exp Metastasis       Date:  2012-08-15       Impact factor: 5.150

5.  Methylation-associated silencing of MicroRNA-335 contributes tumor cell invasion and migration by interacting with RASA1 in gastric cancer.

Authors:  Zhengrong Li; Daojiang Li; Guoyang Zhang; Jianbo Xiong; Zhigang Jie; Heping Cheng; Yi Cao; Mengmeng Jiang; Liangqing Lin; Zhibiao Le; Shengxing Tan; Wenyu Zou; Binbin Gong; Shengrong Lin; Ke Yang
Journal:  Am J Cancer Res       Date:  2014-11-19       Impact factor: 6.166

Review 6.  Prognostic molecular biomarkers for cutaneous malignant melanoma.

Authors:  Ryo Tanaka; Kazuo Koyanagi; Norihiko Narita; Christine Kuo; Dave S B Hoon
Journal:  J Surg Oncol       Date:  2011-05-09       Impact factor: 3.454

7.  Toward a drug development path that targets metastatic progression in osteosarcoma.

Authors:  Chand Khanna; Timothy M Fan; Richard Gorlick; Lee J Helman; Eugenie S Kleinerman; Peter C Adamson; Peter J Houghton; William D Tap; Danny R Welch; Patricia S Steeg; Glenn Merlino; Poul H B Sorensen; Paul Meltzer; David G Kirsch; Katherine A Janeway; Brenda Weigel; Lor Randall; Stephen J Withrow; Melissa Paoloni; Rosandra Kaplan; Beverly A Teicher; Nita L Seibel; Malcolm Smith; Aykut Uren; Shreyaskumar R Patel; Jeffrey Trent; Sharon A Savage; Lisa Mirabello; Denise Reinke; Donald A Barkaukas; Mark Krailo; Mark Bernstein
Journal:  Clin Cancer Res       Date:  2014-05-06       Impact factor: 12.531

8.  A new role for cortactin in invadopodia: regulation of protease secretion.

Authors:  Emily S Clark; Alissa M Weaver
Journal:  Eur J Cell Biol       Date:  2008-03-14       Impact factor: 4.492

9.  Exocyst complex component Sec8: a presumed component in the progression of human oral squamous-cell carcinoma by secretion of matrix metalloproteinases.

Authors:  Ayumi Yamamoto; Atsushi Kasamatsu; Shunsaku Ishige; Kazuyuki Koike; Kengo Saito; Yukinao Kouzu; Hirofumi Koike; Yosuke Sakamoto; Katsunori Ogawara; Masashi Shiiba; Hideki Tanzawa; Katsuhiro Uzawa
Journal:  J Cancer Res Clin Oncol       Date:  2012-12-04       Impact factor: 4.553

Review 10.  A "class action" against the microenvironment: do cancer cells cooperate in metastasis?

Authors:  François-Clément Bidard; Jean-Yves Pierga; Anne Vincent-Salomon; Marie-France Poupon
Journal:  Cancer Metastasis Rev       Date:  2008-03       Impact factor: 9.264

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