Literature DB >> 16769681

Multi-protein complexes at the beta-globin locus.

Milind C Mahajan1, Sherman M Weissman.   

Abstract

Biochemical analysis of the beta-globin gene function has led to the identification of several multi-protein complexes at the locus control region (LCR), insulator and promoters. This review briefly summarizes these multi-protein complexes and discusses their contribution towards the regulation of the beta-globin gene expression.

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Year:  2006        PMID： 16769681     DOI： 10.1093/bfgp/ell001

Source DB:  PubMed          Journal:  Brief Funct Genomic Proteomic        ISSN： 1473-9550


  5 in total

1.  Fragile regions and not functional constraints predominate in shaping gene organization in the genus Drosophila.

Authors:  Marcin von Grotthuss; Michael Ashburner; José M Ranz
Journal:  Genome Res       Date:  2010-07-02       Impact factor: 9.043

2.  Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the beta-globin locus.

Authors:  Tanushri Sengupta; Ken Chen; Eric Milot; James J Bieker
Journal:  Mol Cell Biol       Date:  2008-08-18       Impact factor: 4.272

3.  Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma.

Authors:  Byung Hee Koh; Soo Seok Hwang; Joo Young Kim; Wonyong Lee; Min-Jong Kang; Chun Geun Lee; Jung-Won Park; Richard A Flavell; Gap Ryol Lee
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-18       Impact factor: 11.205

4.  Females and males contribute in opposite ways to the evolution of gene order in Drosophila.

Authors:  Carlos Díaz-Castillo
Journal:  PLoS One       Date:  2013-05-16       Impact factor: 3.240

5.  Global chromatin domain organization of the Drosophila genome.

Authors:  Elzo de Wit; Ulrich Braunschweig; Frauke Greil; Harmen J Bussemaker; Bas van Steensel
Journal:  PLoS Genet       Date:  2008-03-28       Impact factor: 5.917
  5 in total

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