Literature DB >> 167695

[Microadenomas and hypersecreting pituitary adenomas].

J L Vézina, J Hardy, M Yamashita.   

Abstract

The early radiographic changes of the sella turcica in the cases of hypersecreting pituitary adenomas (Cushing disease, acromegaly, amenorrhea-galactorrhea) are reported and discussed. The finding of the double contour of the sellar floor and the small crescentic bulging of its antero-inferior wall, with the aid of the tomographic cuts of the sella, has permited the diagnosis of the microadenoma'a localization. With this it si possible the achievement of a selective excision of the lesion in the initial stage, when the tumor has not caused yet irreversible damage to the inside normal pituitary tissue. This surgery is performed in the precocious stage with the primary goal to preserve the normal gland, without hurt it to avoid postoperative hipopituitarism. A anatomo-radiologic classification of the alterations sella turcica in 4 grades is made, which is of great utility for the surgical prognostic, since we have observed clinical and biological cure over 90% in the grade 1, 75% in the grade 2, 50% in the grade 3 and up to 10% in the grade 4 in the first surgery.

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Year:  1975        PMID: 167695     DOI: 10.1590/s0004-282x1975000200002

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  4 in total

Review 1.  Epidemiology, clinical presentation and diagnosis of non-functioning pituitary adenomas.

Authors:  Georgia Ntali; John A Wass
Journal:  Pituitary       Date:  2018-04       Impact factor: 4.107

2.  Low expression of secreted frizzled-related protein 2 and nuclear accumulation of β-catenin in aggressive nonfunctioning pituitary adenoma.

Authors:  Youtu Wu; Jiwei Bai; Linchuan Hong; Chunhui Liu; Shengyuan Yu; Guoqiang Yu; Yazhuo Zhang
Journal:  Oncol Lett       Date:  2016-05-13       Impact factor: 2.967

3.  Contribution of molecular analysis to the typification of the non-functioning pituitary adenomas.

Authors:  Laura Sanchez-Tejada; Ruth Sanchez-Ortiga; Cristina Lamas; Rosa Camara; Pedro Riesgo; Carmen Fajardo; Francisco Ignacio Aranda; Antonio Pico
Journal:  PLoS One       Date:  2017-07-10       Impact factor: 3.240

4.  Clinical Features, Therapeutic Trends, and Outcome of Giant Prolactinomas: A Single-Center Experience Over a 12-Year Period.

Authors:  Mussa H Almalki; Naji Aljohani; Saad Alzahrani; Ohoud Almohareb; Maswood M Ahmad; Abdullah A Alrashed; Fahad Alshahrani; Badurudeen Mahmood Buhary
Journal:  Clin Med Insights Endocrinol Diabetes       Date:  2020-06-04
  4 in total

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