| Literature DB >> 16769398 |
Joel R Lim1, Philip R Faught, Naga P Chalasani, Jean P Molleston.
Abstract
Two children presented with acute hepatitis after starting therapy with atomoxetine (Strattera). In one child, no competing diagnosis could be identified, and liver injury resolved completely on withdrawal of the medication. In the second child, the evaluation was suggestive of type 1 autoimmune hepatitis; she subsequently improved with removal of atomoxetine and concomitant immunosuppressive therapy. Atomoxetine may cause clinically significant hepatotoxicity either by metabolic idiosyncrasy or by inducing autoimmune hepatitis.Entities:
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Year: 2006 PMID： 16769398 DOI： 10.1016/j.jpeds.2006.01.035
Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406